Ricketts S W, Alonso S
Beaufort Cottage Stables, Newmarket, Suffolk, UK.
Equine Vet J. 1991 May;23(3):185-8. doi: 10.1111/j.2042-3306.1991.tb02751.x.
Paired endometrial biopsy samples were taken from 530 subfertile mares, before and after treatment (where indicated) and a period of sexual rest. Prognoses were made after each biopsy (Categories 1A-4A before treatment and Categories 1B-4B after treatment), using histopathological criteria similar to those described by Kenney and Doig (1986). Eighty-seven per cent of the mares were assigned to first biopsy prognosis Category 3A. The second biopsy prognosis produced a more even population distribution (10, 47, 40 and 3 per cent respectively for Category 1B, 2B, 3B and 4B mares). First biopsy Category 3A and 4A mares produced mean foaling rates of 51 and 40 per cent respectively. None of the 14 second biopsy Category 4B mares delivered a live foal (12 were barren, one aborted and one suffered early foetal death). This study supports the hypothesis that a breeding prognosis assigned on the basis of two endometrial biopsy samples, taken before and after specific uterine treatment, where indicated, which takes into consideration the mare's ability to respond to treatment, is likely to be more accurate than one assigned after a single biopsy sample.
从530匹不育母马身上采集配对的子宫内膜活检样本，分别在治疗前后（如适用）以及一段性休息期进行。每次活检后进行预后评估（治疗前为1A - 4A类别，治疗后为1B - 4B类别），使用与Kenney和Doig（1986年）描述的类似的组织病理学标准。87%的母马首次活检预后被归为3A类别。第二次活检预后产生了更均匀的群体分布（1B、2B、3B和4B类别的母马分别为10%、47%、40%和3%）。首次活检为3A和4A类别的母马平均产驹率分别为51%和40%。第二次活检为4B类别的14匹母马中没有一匹产下活驹（12匹不育，一匹流产，一匹早期胎儿死亡）。本研究支持这样的假设，即根据特定子宫治疗前后（如适用）采集的两份子宫内膜活检样本进行的繁殖预后评估，考虑到母马对治疗的反应能力，可能比单次活检样本后的评估更准确。
