Müller Jörg, Janssen Thomas
Hals-Nasen-Ohrenklinik, Technische Universität München, Ismaningerstrasse 22, D-81675 Munich, Germany.
Hear Res. 2008 Dec;246(1-2):9-22. doi: 10.1016/j.heares.2008.09.005. Epub 2008 Sep 25.
The aim of this study was to investigate whether distortion product otoacoustic emissions (DPOAEs) are a suitable means for detecting small changes in cochlear amplifier functionality due to occupational noise exposure of one workday and whether efferent reflex strength of the medial olivocochlear bundle is able to predict the ear's susceptibility to noise. High-resolution (Deltaf(2)= 47 Hz) DPOAEs were recorded between 3.5 and 4.5 kHz at close-to-threshold primary tone levels. For comparison, pure-tone audiometry was conducted. Efferent reflex strength was measured by means of DPOAEs at a specific frequency with and without contralateral acoustic stimulation. A statistically significant change was found for pure-tone thresholds (DeltaL(ht)=+1.6+/-3.0 dB, n=155) and DPOAE levels (DeltaL(dp)=-1.0+/-2.4 dB, n=646; L(2)=20 dB SPL) in factory workers but not in office workers (DeltaL(ht)=-1.3+/-3.3 dB, n=80; DeltaL(dp)=0.0+/-1.6 dB, n=336) (control group). However, the influence of systematic biases due to, e.g. ear probe calibration or measurement sequence effects, has to be considered. Moreover, there was no significant correlation between efferent reflex strength and shifts in pure-tone thresholds or shifts in DPOAE levels. Thus, the applied measures of efferent reflex strength do not seem to be suitable for predicting temporary changes in hearing capability.
本研究的目的是调查畸变产物耳声发射(DPOAE)是否是检测由于一个工作日的职业噪声暴露导致的耳蜗放大器功能微小变化的合适手段,以及内侧橄榄耳蜗束的传出反射强度是否能够预测耳朵对噪声的易感性。在接近阈值的初级音调水平下,于3.5至4.5kHz之间记录高分辨率(Deltaf(2)=47Hz)的DPOAE。作为比较,进行了纯音听力测定。通过在特定频率下有无对侧声刺激时的DPOAE来测量传出反射强度。在工厂工人中发现纯音阈值(DeltaL(ht)=+1.6+/-3.0dB,n=155)和DPOAE水平(DeltaL(dp)=-1.0+/-2.4dB,n=646;L(2)=20dB SPL)有统计学上的显著变化,但在办公室工作人员(对照组,DeltaL(ht)=-1.3+/-3.3dB,n=80;DeltaL(dp)=0.0+/-1.6dB,n=336)中未发现。然而,必须考虑诸如耳探头校准或测量顺序效应等系统偏差的影响。此外,传出反射强度与纯音阈值变化或DPOAE水平变化之间没有显著相关性。因此,所应用的传出反射强度测量方法似乎不适用于预测听力能力的暂时变化。