Kazokoglu Haluk, Onal Sumru, Tugal-Tutkun Ilknur, Mirza Ertugrul, Akova Yonca, Ozyazgan Yilmaz, Soylu Merih, Batioglu Figen, Apaydin Cemil
Department of Ophthalmology, Marmara University School of Medicine, Istanbul, Turkey.
Ophthalmic Epidemiol. 2008 Sep-Oct;15(5):285-93. doi: 10.1080/09286580802262821.
To analyze the referral patterns and clinical features of uveitis in tertiary eye care centers in Turkey.
Uveitis services of eight university clinics collected data on uveitis patients who presented during 2004. Data were collected on a form including a questionnaire on socio-demographic and clinical features which were documented at presentation.
A total of 761 patients (1187 eyes) with a mean age of 35.5 years were included in the study. Male to female ratio was 1.04:1. The majority of patients (89.6%) were from an urban population, 53% were referrals and 43% had had uveitis for more than one year. The most common type of uveitis was anterior uveitis (52.5%) followed by panuveitis (28.1%), posterior uveitis (12.7%) and intermediate uveitis (6.7%). In 56.8% of patients an etiological classification was established. The most common etiology was Behcet's disease (32.1%), followed by Fuchs' heterochromic iridocyclitis (5.1%) and ocular toxoplasmosis (4.7%). Among 48 pediatric patients uveitis associated with juvenile idiopathic arthritis and ocular toxoplasmosis both having equal frequencies (12.5%) were the most common diagnosis. These were followed by Behcet's disease with juvenile-onset (10.4%). At the time of presentation, 6.25% of the patients were legally blind (having visual acuity less than 0.1 in the better seeing eye).
Compared to the uveitis series reported from other countries, Behcet uveitis was the leading cause of uveitis in this series. Uveitis associated with juvenile idiopathic arthritis and ocular toxoplasmosis were the most common cause of uveitis in childhood. On the other hand, entities like acquired immunodeficiency syndrome-related uveitis, presumed ocular histoplasmosis and Birdshot retinochoroidopathy were rare.
分析土耳其三级眼科护理中心葡萄膜炎的转诊模式和临床特征。
八所大学诊所的葡萄膜炎服务部门收集了2004年期间前来就诊的葡萄膜炎患者的数据。数据通过一份表格收集,该表格包含一份关于社会人口统计学和临床特征的问卷,这些特征在就诊时记录在案。
共有761例患者(1187只眼)纳入研究,平均年龄35.5岁。男女比例为1.04:1。大多数患者(89.6%)来自城市人口,53%为转诊患者,43%患有葡萄膜炎超过一年。最常见的葡萄膜炎类型是前葡萄膜炎(52.5%),其次是全葡萄膜炎(28.1%)、后葡萄膜炎(12.7%)和中间葡萄膜炎(6.7%)。56.8%的患者建立了病因分类。最常见的病因是白塞病(32.1%),其次是富克斯异色性虹膜睫状体炎(5.1%)和眼弓形虫病(4.7%)。在48例儿科患者中,与幼年特发性关节炎相关的葡萄膜炎和眼弓形虫病的发病率相同(均为12.5%),是最常见的诊断。其次是幼年型白塞病(10.4%)。就诊时,6.25%的患者法定失明(较好眼视力低于0.1)。
与其他国家报道的葡萄膜炎系列相比,白塞葡萄膜炎是本系列中葡萄膜炎的主要原因。与幼年特发性关节炎和眼弓形虫病相关的葡萄膜炎是儿童葡萄膜炎最常见的原因。另一方面,获得性免疫缺陷综合征相关葡萄膜炎、推测性眼组织胞浆菌病和鸟枪弹样视网膜脉络膜病变等疾病较为罕见。