Chalam K V, Keshavamurthy R, Brar V S
University of Florida College of Medicine, Department of Ophthalmology, Jacksonville, FL 32204, USA.
Eur J Ophthalmol. 2008 Sep-Oct;18(5):831-3. doi: 10.1177/112067210801800530.
Cystoid macular edema is one of the important causes of visual loss in branch retinal vein occlusion. Proximity of the cyst to the external limiting membrane and disruption of the layer on time domain optical coherence tomography is associated with poor final visual outcomes. The authors describe pre- and post-intravitreal bevacizumab spectral domain optical coherence tomography features in a case of cystoid macular edema associated with branch retinal vein occlusion that was resolved after treatment with intravitreal bevacizumab.
A 50-year-old woman was diagnosed with cystoid macular edema due to branch retinal vein occlusion and underwent intravitreal injection with bevacizumab after the primary treatment with laser photocoagulation failed.
The patient's visual acuity recovered from 20/40 to 20/20. Spectral domain optical coherence tomography documented complete resolution of a large foveal cyst (150 micronm by 280 micronm) and recovery of the discontinuity of the external limiting membrane 1 week after treatment.
Spectral domain optical coherence tomography is a useful tool in identifying the ultrastructural changes associated with cystoid macular edema associated with branch retinal vein occlusion and identifying the possible factors involved in prognosticating visual outcome after effective treatment.
黄斑囊样水肿是视网膜分支静脉阻塞导致视力丧失的重要原因之一。囊肿与外界膜的接近程度以及在时域光学相干断层扫描上该层的破坏与最终视力不佳相关。作者描述了1例与视网膜分支静脉阻塞相关的黄斑囊样水肿患者在玻璃体腔内注射贝伐单抗治疗前后的频域光学相干断层扫描特征,该患者经玻璃体腔内注射贝伐单抗治疗后水肿消退。
一名50岁女性因视网膜分支静脉阻塞被诊断为黄斑囊样水肿,在激光光凝初步治疗失败后接受了玻璃体腔内贝伐单抗注射。
患者视力从20/40恢复到20/20。频域光学相干断层扫描显示治疗1周后,一个大的黄斑中心凹囊肿(150微米×280微米)完全消退,外界膜的连续性恢复。
频域光学相干断层扫描是一种有用的工具,可用于识别与视网膜分支静脉阻塞相关的黄斑囊样水肿的超微结构变化,并确定有效治疗后预测视力预后的可能因素。