Menchón S A, Condat C A
CONICET and FaMAF, Universidad Nacional de Córdoba, 5000-Córdoba, Argentina.
Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Aug;78(2 Pt 1):022901. doi: 10.1103/PhysRevE.78.022901. Epub 2008 Aug 8.
Simulations of avascular cancer growth are performed using experimental values of the relevant parameters. This permits a realistic assessment of the influence of these parameters on cancer growth dynamics. In general, an early exponential growth phase is followed by a linear regime (as observed in recent experiments), while the thickness of the viable cell layer remains approximately constant. Contrary to some predictions, a transition to latency is not observed.
使用相关参数的实验值对无血管癌生长进行模拟。这使得能够对这些参数对癌症生长动力学的影响进行现实评估。一般来说，早期指数增长阶段之后是线性阶段（如最近的实验中所观察到的），而活细胞层的厚度大致保持恒定。与一些预测相反，未观察到向潜伏期的转变。
