Cutler Jeffrey A, Sorlie Paul D, Wolz Michael, Thom Thomas, Fields Larry E, Roccella Edward J
US Department of Health and Human Services, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Hypertension. 2008 Nov;52(5):818-27. doi: 10.1161/HYPERTENSIONAHA.108.113357. Epub 2008 Oct 13.
This study assesses trends in hypertension prevalence, blood pressure distributions and mean levels, and hypertension awareness, treatment, and control among US adults, age >or=18 years, between the third National Health and Nutrition Examination Survey (1988-1994) and the 1999-2004 National Health and Nutrition Examination Survey, a period of approximately 10 years. The age-standardized prevalence rate increased from 24.4% to 28.9% (P<0.001), with the largest increases among non-Hispanic women. Depending on gender and race/ethnicity, from one fifth to four fifths of the increase could be accounted for by increasing body mass index. Among hypertensive persons, there were modest increases in awareness (P=0.04), from 68.5% to 71.8%. The rate for men increased from 61.6% to 69.3% (P=0.001), whereas the rate for women did not change significantly. Rates remained higher for women than for men, although the difference narrowed considerably. Improvements in treatment and control rates were larger: 53.1% to 61.4% and 26.1% to 35.1%, respectively (both P<0.001). The greatest increases occurred among non-Hispanic white men and non-Hispanic black persons, especially men. Mexican American persons showed improvement in treatment and control rates, but these rates remained the lowest among race/ethnic subgroups (47.4% and 24.3%, respectively). Among all of the race/ethnic groups, women continued to have somewhat better awareness, treatment, and control, except for control rates among non-Hispanic white persons, which became higher in men. Differences between non-Hispanic black and white persons in awareness, treatment, and control were small. These divergent trends may translate into disparate trends in cardiovascular disease morbidity and mortality.
本研究评估了年龄≥18岁的美国成年人在第三次全国健康与营养检查调查(1988 - 1994年)和1999 - 2004年全国健康与营养检查调查之间约10年时间里高血压患病率、血压分布及平均水平,以及高血压知晓率、治疗率和控制率的变化趋势。年龄标准化患病率从24.4%升至28.9%(P<0.001),非西班牙裔女性增幅最大。根据性别和种族/族裔,五分之一至五分之四的增幅可归因于体重指数的增加。在高血压患者中,知晓率有适度提高(P = 0.04),从68.5%升至71.8%。男性知晓率从61.6%升至69.3%(P = 0.001),而女性知晓率无显著变化。女性知晓率仍高于男性,尽管差距大幅缩小。治疗率和控制率的改善幅度更大:分别从53.1%升至61.4%和从26.1%升至35.1%(均P<0.001)。增幅最大的是非西班牙裔白人男性和非西班牙裔黑人,尤其是男性。墨西哥裔美国人的治疗率和控制率有所改善,但在所有种族/族裔亚组中仍最低(分别为47.4%和24.3%)。在所有种族/族裔群体中,除了非西班牙裔白人的控制率男性高于女性外,女性在知晓率、治疗率和控制率方面仍略胜一筹。非西班牙裔黑人和白人在知晓率、治疗率和控制率方面的差异较小。这些不同的趋势可能会转化为心血管疾病发病率和死亡率的不同趋势。