Martínez-Ortega José M, Jurado Dolores, Gurpegui Manuel
Psychiatry and Neurosciences Research Group (CTS-549), Institute of Neurosciences, University of Granada, and Psychiatry Service, Virgen de las Nieves University Hospital, Granada, Spain.
Prog Neuropsychopharmacol Biol Psychiatry. 2008 Dec 12;32(8):1972-7. doi: 10.1016/j.pnpbp.2008.09.015. Epub 2008 Sep 30.
As an indication of potential psychopathology, our aim was to compare, in a non-psychiatric sample, the variables associated to daily smoking with those associated to nicotine dependence. We also compared dependent and non-dependent smokers on these variables and on the age of onset of daily smoking (AODS).
A sample of 290 persons aged 18 or older, recruited in a family medical clinic, were interviewed to inquire about their tobacco, caffeine, alcohol, and illegal drugs consumption, and on their practice of physical exercise. Psychiatric morbidity was assessed with the General Health Questionnaire (GHQ-28) and defined by a score>6. They also were questioned on their use of psychotropic medication and previous suicide attempt. The smokers answered the Fagerström Test for Nicotine Dependence (FTND) and the question on their age of onset of daily smoking (AODS).
In comparison with non-dependent smoking, nicotine dependence was associated with current use of psychotropic medication, psychiatric morbidity, previous suicide attempt, and earlier AODS. Logistic regression analyses showed that nicotine dependence was associated with antecedents of suicide attempt and primary or lower education as well as with high caffeine use and the regular use of illegal drugs; in contrast, daily smoking showed a significant association with high caffeine use, the regular use of illegal drugs and lack of physical exercise.
In terms of psychopathology or behavioral disturbance-particularly attempting suicide-nicotine dependence adds significant information as opposed to the simple daily smoking, with important implications in clinical and epidemiological psychiatric studies.
作为潜在精神病理学的一种指征,我们的目的是在一个非精神科样本中,比较与每日吸烟相关的变量和与尼古丁依赖相关的变量。我们还比较了依赖和非依赖吸烟者在这些变量以及每日吸烟起始年龄(AODS)方面的差异。
在一家家庭医疗诊所招募了290名18岁及以上的人员作为样本,对他们进行访谈,询问他们的烟草、咖啡因、酒精和非法药物消费情况以及体育锻炼习惯。使用一般健康问卷(GHQ - 28)评估精神疾病发病率,得分>6则定义为患有精神疾病。还询问了他们使用精神药物的情况和既往自杀未遂情况。吸烟者回答尼古丁依赖的法格斯特罗姆测试(FTND)以及关于他们每日吸烟起始年龄(AODS)的问题。
与非依赖吸烟相比,尼古丁依赖与当前使用精神药物、精神疾病发病率、既往自杀未遂以及更早的AODS相关。逻辑回归分析表明,尼古丁依赖与自杀未遂史、小学或更低学历以及高咖啡因摄入量和经常使用非法药物有关;相比之下,每日吸烟与高咖啡因摄入量、经常使用非法药物和缺乏体育锻炼有显著关联。
在精神病理学或行为障碍方面——特别是自杀未遂——尼古丁依赖相对于单纯的每日吸烟增加了重要信息,这在临床和流行病学精神科研究中有重要意义。