Park Jisu, Kim Sung Hong, Lee Phil Ho
National Research Laboratory for Catalytic Organic Reaction, Department of Chemistry, and Institute for Molecular Science and Fusion Technology, Kangwon National University, Chuncheon 200-701, Republic of Korea.
Org Lett. 2008 Nov 6;10(21):5067-70. doi: 10.1021/ol802073q. Epub 2008 Oct 15.
A highly selective synthetic method of functionalized vinyl allenols was developed from the reactions of various carbonyl compounds with organoindium reagent in situ generated from indium and 1-bromopent-4-en-2-yne derivatives. Treatment of vinyl allenols with gold catalyst, dienophile, or indium trihalide produced the functionalized dihydrofuran, cyclohexene, or 2-halo-1,3-diene derivatives in good to excellent yields.
