Veljkovic Nevena, Glisic Sanja, Prljic Jelena, Perovic Vladimir, Botta Maurizio, Veljkovic Veljko
Center for Multidisciplinary Research, Institute of Nuclear Sciences VINCA, Belgrade, Serbia.
Curr Protein Pept Sci. 2008 Oct;9(5):493-506. doi: 10.2174/138920308785915245.
The field of bioinformatics has become a major part of the drug discovery pipeline playing a key role in improvement and acceleration of this time and money consuming process. Here we review the application of the informational spectrum method (ISM), a virtual spectroscopy method for structure/function analysis of proteins, in identification of functional protein domains representing candidate therapeutic targets for drugs against human immunodeficiency virus (HIV)-1, anthrax, highly pathogenic influenza virus H5N1 and cardiovascular diseases.
