Aoki N, Shimizu N, Ito M, Yamamoto A, Takenouchi T, Matsumura G, Sato Y
Department of Dermatology, Niigata University School of Medicine.
Nihon Hifuka Gakkai Zasshi. 1991 Mar;101(4):469-72.
A 15-month-old girl had an asymptomatic eruption of yellowish-brown flat papules of 12 months' duration. Those papules were seen multiply on her face and in a small number on her neck and trunk. Skin biopsy showed a massive infiltrate of histiocytic cells in the upper and middle dermis. Electron microscopically, these cells had comma-shaped bodies in the cytoplasm, and formed desmosome-like junctions at the cell peripheries. A diagnosis of benign cephalic histiocytosis was made on the basis of these clinical, histological, and ultrastructural findings. To the best of our knowledge, this is the first report of benign cephalic histiocytosis in Japan.
一名15个月大的女童出现无症状的黄棕色扁平丘疹皮疹，病程12个月。这些丘疹在她的面部多处可见，颈部和躯干有少量。皮肤活检显示真皮上部和中部有大量组织细胞浸润。电子显微镜下，这些细胞的细胞质中有逗号形小体，并在细胞周边形成类似桥粒的连接。根据这些临床、组织学和超微结构检查结果，诊断为良性头部组织细胞增生症。据我们所知，这是日本首例良性头部组织细胞增生症的报告。
