Peña-Penabad C, Unamuno P, Garcia-Silva J, Ludeña M D, Armijo M
Department of Dermatology, University Hospital, Salamanca, Spain.
Pediatr Dermatol. 1994 Jun;11(2):164-7. doi: 10.1111/j.1525-1470.1994.tb00573.x.
A 3-year-old boy had maculopapules on his face and neck since age 6 months. These were yellow-brown, asymptomatic, and clinically similar to flat warts. Histopathologic study revealed a fibrohistiocytic infiltrate in the superficial dermis. Ultrastructurally, comma-shaped bodies, desmosome-like junctions, and coated vesicles were seen; there were no lipid droplets or Birbeck granules. With these data, a diagnosis of benign cephalic histiocytosis was made. Twenty-five cases are reported in the literature: 17 males and 8 females (male:female ratio 2:1). Sixteen patients had lesions on parts of the body other than the head, neck, and shoulders.
