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水果和蔬菜是半乳糖的一个来源:对半乳糖血症患者饮食规划的启示。

Fruits and vegetables are a source of galactose: implications in planning the diets of patients with galactosaemia.

作者信息

Gross K C, Acosta P B

机构信息

United States Department of Agriculture, Agricultural Research Service, Product Quality and Development Institute, Beltsville, MD 20705.

出版信息

J Inherit Metab Dis. 1991;14(2):253-8. doi: 10.1007/BF01800599.

DOI:10.1007/BF01800599
PMID:1886408
Abstract

It has become apparent that removing dairy products from the diets of patients with galactosaemia does not sufficiently diminish the deleterious signs. We have determined the amount of soluble monomeric galactose in 45 fruits and vegetables using capillary gas chromatography and selective ion monitoring. Galactose contents ranged from less than 0.1 mg per 100 g of tissue in artichoke, mushroom, olive, and peanut to 35.4 mg per 100 g in persimmon. Fruits and vegetables with over 10 mg per 100 g included date, papaya, bell pepper, tomato and watermelon. These results will provide important data for planning the diets of patients with galactosaemia.

摘要

显然,从半乳糖血症患者的饮食中去除乳制品并不能充分减轻有害症状。我们使用毛细管气相色谱法和选择性离子监测法测定了45种水果和蔬菜中可溶性单体半乳糖的含量。半乳糖含量范围从每100克朝鲜蓟、蘑菇、橄榄和花生组织中低于0.1毫克到每100克柿子中35.4毫克。每100克中半乳糖含量超过10毫克的水果和蔬菜包括枣、木瓜、甜椒、番茄和西瓜。这些结果将为规划半乳糖血症患者的饮食提供重要数据。

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本文引用的文献

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Changes in the cell wall of the pear during ripening.梨在成熟过程中细胞壁的变化。
Biochem J. 1956 Sep;64(1):123-32. doi: 10.1042/bj0640123.
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Phenolic components of the primary cell wall. Feruloylated disaccharides of D-galactose and L-arabinose from spinach polysaccharide.初生细胞壁的酚类成分。菠菜多糖中D-半乳糖和L-阿拉伯糖的阿魏酰化二糖。
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A Catalog of Natural Products Occurring in Watermelon-.西瓜中天然产物目录。
Front Nutr. 2021 Sep 14;8:729822. doi: 10.3389/fnut.2021.729822. eCollection 2021.
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Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors.基于结构的小分子人半乳糖激酶抑制剂优化。
J Med Chem. 2021 Sep 23;64(18):13551-13571. doi: 10.1021/acs.jmedchem.1c00945. Epub 2021 Sep 7.
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Galactose-Induced Skin Aging: The Role of Oxidative Stress.半乳糖诱导的皮肤衰老:氧化应激的作用。
Oxid Med Cell Longev. 2020 Jun 17;2020:7145656. doi: 10.1155/2020/7145656. eCollection 2020.
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A Trace Amount of Galactose, a Major Component of Milk Sugar, Allows Maturation of Glycoproteins during Sugar Starvation.痕量半乳糖(乳糖的主要成分)可使糖蛋白在糖饥饿期间成熟。
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Dietary saccharides and sweet tastants have differential effects on colonization of oocytes by endosymbionts.膳食糖类和甜味剂对内共生菌在卵母细胞中的定殖具有不同影响。
Biol Open. 2017 Jul 15;6(7):1074-1083. doi: 10.1242/bio.023895.
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Sweet and sour: an update on classic galactosemia.酸甜:经典半乳糖血症的最新进展
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10
Hsp90 Maintains Proteostasis of the Galactose Utilization Pathway To Prevent Cell Lethality.热休克蛋白90维持半乳糖利用途径的蛋白质稳态以防止细胞死亡。
Mol Cell Biol. 2016 Apr 15;36(9):1412-24. doi: 10.1128/MCB.01064-15. Print 2016 May.