Portnoi P A, MacDonald A
Medical Advisory Panel, Galactosaemia Support Group UK, West Midlands, UK.
J Hum Nutr Diet. 2009 Oct;22(5):400-8. doi: 10.1111/j.1365-277X.2009.00948.x.
Treatment of galactosaemia requires a low galactose diet. In the UK, traditionally, all cheeses have been excluded from the diet, although some types of mature hard cheese are likely to be low in lactose and galactose. The present study aimed to determine the lactose and galactose content of mature cheeses.
Over 6 years, the UK Galactosaemia Support Group commissioned the analysis of 109 samples (by two laboratories) of 12 cheese types, in eight batches throughout the year. Cheeses, obtained from retail outlets, were homogenised, sugars were extracted using water or 40% alcohol for fatty samples, and samples were deproteinised. Enzymatic analysis using measuring light absorbance was conducted on filtered extracts.
Cheeses containing undetectable quantities of lactose (<2.8 mg 100 g(-1), Leatherhead Food International, Leatherhead, UK (LFI) analysis; <10 mg 100 g(-1), Laboratory of Government Chemist, Teddington, UK (LGC Limited) analysis) and galactose were: Gruyere (five samples); Emmental (block, sliced and grated) (16 samples); Jarlsberg (six samples); Parmigiano Reggiano and Grana Padano Italian Parmesan (block and grated) (16 samples); and mature Cheddar cheese from the UK West Country Farmhouse Cheese Makers Association (35 samples) only. Lactose containing cheeses included other mature Cheddar cheeses, Gouda and Edam.
Gruyere, Emmental, Jarlsberg, Italian Parmesan (Parmigiano Reggiano and Grana Padano), and mature Cheddar cheese produced in one area of England where the manufacturing process is standardised and guaranteed are now allowed in the UK galactosaemia diet.
半乳糖血症的治疗需要低半乳糖饮食。在英国,传统上所有奶酪都被排除在饮食之外,尽管某些类型的成熟硬奶酪可能乳糖和半乳糖含量较低。本研究旨在确定成熟奶酪中的乳糖和半乳糖含量。
在6年多的时间里,英国半乳糖血症支持小组委托(两个实验室)对全年8批12种奶酪类型的109个样本进行分析。从零售店获取的奶酪被均质化,对于含脂肪的样本,用水或40%酒精提取糖分,然后对样本进行脱蛋白处理。对过滤后的提取物进行酶法分析,通过测量吸光度来测定。
乳糖含量不可检测(<2.8毫克/100克,英国莱瑟黑德食品国际公司(LFI)分析;<10毫克/100克,英国特丁顿政府化学家实验室(LGC有限公司)分析)且半乳糖含量不可检测的奶酪有:格律耶尔奶酪(5个样本);埃曼塔尔奶酪(块状、切片和磨碎)(16个样本);贾尔斯贝里奶酪(6个样本);帕尔马干酪和意大利格拉纳·帕达诺干酪(块状和磨碎)(16个样本);以及仅来自英国西部乡村农家奶酪制造商协会的成熟切达干酪(35个样本)。含乳糖的奶酪包括其他成熟切达干酪、高达干酪和伊登干酪。
在英国半乳糖血症饮食中,现在允许食用格律耶尔奶酪、埃曼塔尔奶酪、贾尔斯贝里奶酪、意大利帕尔马干酪(帕尔马干酪和格拉纳·帕达诺干酪),以及在英格兰一个制造工艺标准化且有质量保证的地区生产的成熟切达干酪。