Lavandero S, Neira M, López C, Gallardo R, Guerrero E, Rutman M
Laboratory of Biochemistry and Biology, Nutrition and Food Engineering, Santiago, Chile.
Poult Sci. 1991 Jul;70(7):1633-6. doi: 10.3382/ps.0701633.
Fenthion, an irreversible cholinesterase inhibitor, was used to study the role of the cholinergic system on the development of gizzard erosion. Fenthion increases the gizzard erosion score in a dose-dependent manner and this effect became significant at levels higher than .1 ppm (p less than .05). An inverse relationship between plasma cholinesterase activity and pesticide concentration was also observed at doses higher than 1 ppm (P less than .05). These results show the necessity to evaluate organophosphate pesticide levels during the selection of fish meals in poultry.
倍硫磷是一种不可逆的胆碱酯酶抑制剂，被用于研究胆碱能系统在肌胃糜烂发展过程中的作用。倍硫磷以剂量依赖的方式增加肌胃糜烂评分，且在高于0.1 ppm的水平时这种效应变得显著（p小于0.05）。在高于1 ppm的剂量下还观察到血浆胆碱酯酶活性与农药浓度之间呈负相关（P小于0.05）。这些结果表明在家禽鱼粉选择过程中评估有机磷农药水平的必要性。
