[心肌细胞腺苷酸环化酶活性及甲状腺降钙素的作用]
[Myocardial cell adenyl cyclase activity and the effect of thyrocalcitonin].
作者信息
Barabanova V V
出版信息
Fiziol Zh SSSR Im I M Sechenova. 1976 Sep;62(9):1355-60.
PMID:188692
Abstract
The thyrocalcitonin (TCT) effect under influence of some factors affecting the activity of membrane adenylcyclase (AC) of the ventricle myocardial cells in cold-blooded animals, was studied. The TCT positive inotropic effect is intensified by decrease in the potassium concentration in the medium, by blockade of alpha-adrenoreceptors with phentolamine, and inhibited by increase in the potassium concentration and blockade of beta-adrenoreceptors. The TCT action is preserved in presence of adrenaline.
摘要
研究了在一些影响冷血动物心室心肌细胞膜腺苷酸环化酶（AC）活性的因素作用下，甲状腺降钙素（TCT）的效应。培养基中钾浓度降低、用酚妥拉明阻断α-肾上腺素能受体可增强TCT的正性肌力作用，而钾浓度升高和阻断β-肾上腺素能受体则抑制TCT的作用。在肾上腺素存在的情况下，TCT的作用得以保留。
Zotero 插件