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[心得安β-肾上腺素能受体阻滞期间心肌的钙调节激素与功能活动]

[Calcium-regulating hormones and functional activity of the myocardium during beta-adrenoreceptor block by inderal].

作者信息

Barabanova V V, Egorov V Ia

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1985 Dec;71(12):1579-86.

PMID:4092777
Abstract

Effect of calcitonin (CT) upon the AP of contractile cardiomyocytes was absent under conditions of blockade of beta-adrenoreceptors with inderal which reduced the level of intracellular sodium and ionized calcium. Inderal facilitated the effect of parathyroid hormone on the myocardium electrical activity. In conditions of blockade of beta-adrenoreceptors, the CT acted upon the autorhythmic activity of pace-maker cardiomyocytes as in control solution.

摘要

在使用心得安阻断β-肾上腺素能受体从而降低细胞内钠和离子钙水平的情况下,降钙素(CT)对收缩性心肌细胞的动作电位没有影响。心得安促进了甲状旁腺激素对心肌电活动的作用。在β-肾上腺素能受体被阻断的情况下,CT对起搏心肌细胞的自律性活动的作用与在对照溶液中一样。

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