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钩虫(美洲板口线虫)感染与储存铁耗竭。

Hookworm (Necator americanus) infection and storage iron depletion.

作者信息

Pritchard D I, Quinnell R J, Moustafa M, McKean P G, Slater A F, Raiko A, Dale D D, Keymer A E

机构信息

Department of Zoology, University of Nottingham, UK.

出版信息

Trans R Soc Trop Med Hyg. 1991 Mar-Apr;85(2):235-8. doi: 10.1016/0035-9203(91)90038-z.

DOI:10.1016/0035-9203(91)90038-z
PMID:1887481
Abstract

The relationship between iron status and the intensity of infection with hookworm was investigated in a rural population on Karkar Island, Mandang Province, Papua New Guinea. There was a significant negative correlation between plasma ferritin level and hookworm burden, which was strongest in males. In contrast, there was no correlation between plasma ferritin and hookworm egg count, and no consistent correlation between haemoglobin level or haematocrit and either measure of hookworm intensity. The results suggest that the role of hookworm in the aetiology of anaemia may be difficult to assess without the accurate measurement of hookworm burden.

摘要

在巴布亚新几内亚马当省卡尔卡尔岛的农村人口中,研究了铁状态与钩虫感染强度之间的关系。血浆铁蛋白水平与钩虫负荷之间存在显著负相关,在男性中这种相关性最强。相比之下,血浆铁蛋白与钩虫卵计数之间没有相关性,血红蛋白水平或血细胞比容与钩虫感染强度的任何一项指标之间也没有一致的相关性。结果表明,如果不准确测量钩虫负荷,可能难以评估钩虫在贫血病因学中的作用。

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