Sass W, Bräunlich M, Dreyer H P, Matura E, Folberth W, Preismeyer H G, Seifert J
Department of Experimental Surgery, University of Kiel, Germany.
Ultrasound Med Biol. 1991;17(3):239-43. doi: 10.1016/0301-5629(91)90045-x.
Through interpretation of high-speed films at 10,000 frames per second of shock wave action on kidney stones and gallstones, the mechanism of stone destruction was analyzed in detail. This shows that the interaction of the shock wave with the targets firstly produces fissures in the stone material. Liquid then enters these small cracks. The actual disintegration is caused later by the enormous violence of imploding cavitation bubbles within these small split lines. That cavitation acts inside the stone and causes fragmentation even within the human gallbladder could furthermore be demonstrated by using scanning electron microscopy. These results should lead to a different process in gallstone lithotripsy leaving intervals between the shock wave treatments. This will allow the viscous bile fluids to occupy the fissures of the stones more completely and, therefore, should increase the cavitational activity on the subsequent treatment with shock pulses.
通过对每秒10000帧的冲击波作用于肾结石和胆结石的高速影片进行解读，详细分析了结石破坏的机制。这表明冲击波与目标物的相互作用首先在结石材料中产生裂缝。然后液体进入这些小裂缝。实际的崩解随后是由这些小裂缝内空化气泡内爆的巨大力量引起的。通过使用扫描电子显微镜进一步证明了空化作用在结石内部甚至在人体胆囊内都会导致结石破碎。这些结果应该会导致胆结石碎石术采用不同的过程，在冲击波治疗之间留出间隔时间。这将使粘性胆汁液更完全地占据结石的裂缝，因此，在后续的冲击波脉冲治疗中应该会增加空化活性。
