Killeen K P, Libertino J A, Sughayer M A, Lee A K, Watkins E
Department of Urology, Lahey Clinic Medical Center, Burlington, Massachusetts.
Urology. 1991 Sep;38(3):212-5. doi: 10.1016/s0090-4295(91)80346-9.
Retrospective pathologic analysis was conducted of specimens from 88 radical retropubic prostatectomy operations performed between 1982 and 1987 inclusive. The median age of patients was sixty years (range, 46 to 73 years). Of the 88 radical prostatectomies performed, 51 were nerve-sparing (40 bilateral) and 37 were nonnerve-sparing (11 unilateral) procedures. Preoperative clinical staging was similar in both groups. Thirty-five of 37 patients (95%) in nonnerve-staging group and 51 of 51 patients (100%) in nerve-sparing group had clinical Stage B2 disease or less. Pathologic staging in both groups was also similar. In 26 of 37 patients (70%) in nonnerve-sparing group and in 35 of 51 patients (69%) in nerve-sparing group, disease remained localized to the prostate. Both groups were analyzed retrospectively to determine whether or not the incidences of microinvasion of capsule and of extraprostatic disease differed. Review of the apical and lateral margins of the specimens revealed no statistically significant difference in either the degree of microinvasion of capsule or the incidence of extraprostatic disease between the groups.
对1982年至1987年（含）期间进行的88例耻骨后根治性前列腺切除术的标本进行了回顾性病理分析。患者的中位年龄为60岁（范围46至73岁）。在进行的88例根治性前列腺切除术中，51例为保留神经手术（40例双侧），37例为不保留神经手术（11例单侧）。两组术前临床分期相似。不保留神经组的37例患者中有35例（95%），保留神经组的51例患者中有51例（100%）患有临床B2期或更低分期疾病。两组的病理分期也相似。不保留神经组的37例患者中有26例（70%），保留神经组的51例患者中有35例（69%），疾病仍局限于前列腺。对两组进行回顾性分析，以确定包膜微浸润和前列腺外疾病的发生率是否存在差异。对标本的尖部和外侧边缘进行检查发现，两组之间在包膜微浸润程度或前列腺外疾病发生率方面均无统计学显著差异。
