保留神经和不保留神经的耻骨后根治性前列腺切除术后性功能和生活质量的差异。
Differences in sexual function and quality of life after nerve sparing and nonnerve sparing radical retropubic prostatectomy.
作者信息
Gralnek D, Wessells H, Cui H, Dalkin B L
机构信息
Section of Urology, University of Arizona Health Sciences Center, Tucson, USA.
出版信息
J Urol. 2000 Apr;163(4):1166-9; discussion 1169-70.
PURPOSE
We determine the impact of nerve sparing techniques on quality of life after radical retropubic prostatectomy for prostate cancer.
MATERIALS AND METHODS
The RAND/UCLA Prostate Cancer Index and several questions about surgical outcomes, including sexual function, were sent to 170 consecutive patients at least 1 year after radical retropubic prostatectomy. Statistical analysis was performed on data for the entire group as well as subgroups of patients after nerve sparing and nonnerve sparing surgery.
RESULTS
Nonnerve sparing surgery was performed in 83 of 129 responders (nonnerve sparing group) and the remaining 46 were treated with unilateral nerve sparing surgery (nerve sparing group). Scores for sexual function, sexual bother, physical function and physical limitation domains were significantly better in the nerve sparing group. Spontaneous erectile activity was reported by 50% of nerve sparing group patients. Nerve sparing status did not affect urinary function, bowel function or disease outcome.
CONCLUSIONS
Nerve sparing techniques have positive effects on quality of life and sexual function for patients undergoing radical retropubic prostatectomy.
目的
我们确定保留神经技术对前列腺癌耻骨后根治性前列腺切除术后生活质量的影响。
材料与方法
在耻骨后根治性前列腺切除术后至少1年，向170例连续患者发送了兰德/加州大学洛杉矶分校前列腺癌指数以及几个关于手术结果（包括性功能）的问题。对整个组以及保留神经和未保留神经手术患者亚组的数据进行了统计分析。
结果
129例应答者中有83例接受了未保留神经手术（未保留神经组），其余46例接受了单侧保留神经手术（保留神经组）。保留神经组在性功能、性困扰、身体功能和身体限制领域的得分明显更高。保留神经组50%的患者报告有自发勃起活动。保留神经状态不影响排尿功能、肠道功能或疾病结果。
结论
保留神经技术对接受耻骨后根治性前列腺切除术的患者的生活质量和性功能有积极影响。
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