Kochs E, Schulte am Esch J
Abteilung für Anästhesiologie, Krankenhaus Eppendorf, Universität Hamburg.
Anaesthesiol Reanim. 1991;16(3):175-83.
In the present study changes in spontaneous EEG and somatosensory evoked potentials (SEP) under incomplete cerebral ischaemia and in the following reperfusion phase were examined in 8 goats. The neurophysiological parameters were compared with global cerebral blood flow (CBF). At CBF values below 37 ml/100 g/min significant reduction in the EEG power density occurred with a shift of the dominant frequency to lower frequencies. The cortical SEP amplitudes increased significantly with simultaneous increases in latencies. In contrast subcortical components were not affected. In the reperfusion period no complete remission of EEG and SEP changes occurred despite occasional CBF values above the baseline values. The study demonstrates that neurophysiological monitoring can show early functional changes in cases of incomplete cerebral ischaemia.
在本研究中，对8只山羊在不完全性脑缺血及随后的再灌注阶段的自发脑电图（EEG）和体感诱发电位（SEP）变化进行了检查。将神经生理学参数与全脑血流量（CBF）进行了比较。当CBF值低于37 ml/100 g/min时，EEG功率密度显著降低，优势频率向低频转移。皮质SEP波幅显著增加，同时潜伏期延长。相比之下，皮质下成分未受影响。在再灌注期，尽管偶尔CBF值高于基线值，但EEG和SEP变化并未完全缓解。该研究表明，神经生理学监测可以显示不完全性脑缺血病例的早期功能变化。
