Taylor J F, Fluck D, Fluck D
J Clin Pathol. 1976 Dec;29(12):1081-4. doi: 10.1136/jcp.29.12.1081.
Specimens of muscle were obtained from non-suppurating lesions of nine patients with tropical myositis. When examined in an electron microscope, these revealed patchy myocytolysis with loss of band structure. Perimysial cells were also degenerate. Sections from two out of nine patients revealed intracellular vesicles, about 80 nm in diameter, some of which contained 10 nm granules. These vesicles were seen budding from cell membranes and resembled virus particles. The focal necrosis with which they are associated and their absence from control sections support the concept that they are related to the disease process.
从9例热带肌炎患者的非化脓性病变处获取肌肉标本。在电子显微镜下检查时，这些标本显示出片状肌细胞溶解，肌带结构消失。肌束膜细胞也发生变性。9例患者中有2例的切片显示出直径约80纳米的细胞内小泡，其中一些含有10纳米的颗粒。这些小泡可见于从细胞膜上出芽，类似病毒颗粒。它们与之相关的局灶性坏死以及对照切片中不存在这些小泡，支持了它们与疾病过程相关的概念。
