Ertel A, Eng R, Smith S M
Infectious Disease Section, VA Medical Center, East Orange, NJ 07019.
Chest. 1991 Sep;100(3):628-30. doi: 10.1378/chest.100.3.628.
The effect of cigarette smoke on growth of those species of bacteria that are considered common potential human pathogens was examined in vitro. Smoke from both mentholated and nonmentholated cigarettes inhibited the growth of Gram-positive cocci to a greater degree than that of Gram-negative rods. Staphylococcus aureus, Streptococcus pneumoniae, and a variety of other streptococci were inhibited at a smoke solution dilution of 1:8. Enteric bacteria such as Klebsiella, Enterobacter, and Pseudomonas were not affected by a 1:1 dilution of the solution. As with the Gram-positive cocci, the Neisseria species and Branhamella were also inhibited at a dilution of 1:8. Culture results of the mouth of 15 smokers and 15 nonsmokers showed that the smokers have a propensity to develop heavy Gram-negative bacterial colonization.
体外研究了香烟烟雾对那些被视为常见潜在人类病原体的细菌种类生长的影响。薄荷醇香烟和非薄荷醇香烟的烟雾对革兰氏阳性球菌生长的抑制程度大于革兰氏阴性杆菌。在烟雾溶液稀释至1:8时，金黄色葡萄球菌、肺炎链球菌和多种其他链球菌受到抑制。克雷伯菌、肠杆菌和假单胞菌等肠道细菌在溶液1:1稀释时不受影响。与革兰氏阳性球菌一样，奈瑟菌属和布兰汉菌属在稀释至1:8时也受到抑制。15名吸烟者和15名不吸烟者口腔的培养结果表明，吸烟者有形成重度革兰氏阴性菌定植的倾向。
