Wang M L
Department of Neurology Affiliated Hospital Jiamusi Medical College.
Zhonghua Shen Jing Jing Shen Ke Za Zhi. 1991 Jun;24(3):141-3, 187.
The Study on the treatment of 50 cases of subarachnoid hemorrhage (by applying beta-receptor blocking drug propranolol) and the control group of 55 cases revealed that the mortalities of the therapeutic group and the control group were respectively 4% and 9.2% (P less than 0.05) the incidences of the cerebral vasospasm were 2% and 10.6% (P less than 0.01) and those of the abnormal electrocardiograms were 6% and 21.8% (P less than 0.01). The differences between the two group were significant. The function of propranolol may be associated with the sudden increase of catecholamine after subarachnoid haemorrhage and there for the drug has the function of protection of the cardiac muscle and prevention of the cerebral vasospasm.
对50例蛛网膜下腔出血患者（应用β受体阻滞剂普萘洛尔治疗）和55例对照组患者的研究显示，治疗组和对照组的死亡率分别为4%和9.2%（P<0.05），脑血管痉挛发生率分别为2%和10.6%（P<0.01），异常心电图发生率分别为6%和21.8%（P<0.01）。两组之间差异显著。普萘洛尔的作用可能与蛛网膜下腔出血后儿茶酚胺突然增加有关，因此该药物具有保护心肌和预防脑血管痉挛的作用。
