Procházka M, Gazdíková K, Cigánek L, Koprdová I
Neurologická klinika NsP akademika L. Dérera, Bratislava.
Cas Lek Cesk. 1990 Feb 23;129(8):237-9.
Nimodipine, a calcium antagonist, was administered to 33 patients with subarachnoidal haemorrhage as prophylaxis of late ischaemic neurological deficiency. Despite the relatively high frequency of vasospasm during repeated angiographic examinations (27%), the general therapeutic effect in the group of treated patients was favourable. 52% patients improved and had no or only a minimal neurological deficit. Possible mechanisms of the favourable effect of nimodipine in subarachnoidal haemorrhage are mentioned in the discussion.
尼莫地平，一种钙拮抗剂，被用于33例子蛛网膜下腔出血患者，以预防迟发性缺血性神经功能缺损。尽管在重复血管造影检查期间血管痉挛的发生率相对较高（27%），但治疗组的总体治疗效果良好。52%的患者病情改善，无神经功能缺损或仅有轻微神经功能缺损。讨论中提到了尼莫地平在蛛网膜下腔出血中产生良好效果的可能机制。
