Herss Nielsen V A, Pødenphant J, Martens S, Gotfredsen A, Riis B J
Department of Radiology, Glostrup Hospital, University of Copenhagen, Denmark.
Eur J Radiol. 1991 Jul-Aug;13(1):11-4. doi: 10.1016/0720-048x(91)90048-z.
Inter- and intra-observer variation in spine radiographs of 100 osteoporotic women and longitudinal change in roentgenologic status after 1 year of antiosteoporotic treatment were assessed. The method applied was naked eye inspection, and a score system estimating severity of fractures - vertebral deformation score (VDS). Agreement was assessed by the Kappa coefficient corrected for agreement by change. The results showed a satisfactory inter- and intraobserver agreement for wedge (Kappa = 0.72 and 0.90) and compression fractures (Kappa = 0.60 and 0.92). The method proved less reliable for endplate fractures (Kappa = 0.39 and 0.73). We think that the method of investigation is well suited for monitoring treatment effects in longitudinal studies.
评估了100名骨质疏松女性脊柱X光片的观察者间和观察者内差异，以及抗骨质疏松治疗1年后的放射学状态纵向变化。采用的方法是肉眼检查，并使用一种评估骨折严重程度的评分系统——椎体变形评分（VDS）。通过校正变化一致性的Kappa系数评估一致性。结果显示，对于楔形骨折（Kappa分别为0.72和0.90）和压缩性骨折（Kappa分别为0.60和0.92），观察者间和观察者内一致性令人满意。该方法对终板骨折的可靠性较低（Kappa分别为0.39和0.73）。我们认为该调查方法非常适合在纵向研究中监测治疗效果。
