无细菌生长情况下的噬菌体形成；碘乙酸盐、氟化物、短杆菌肽和叠氮化物对噬菌体形成的影响。
Bacteriophage formation without bacterial growth; the effect of iodoacetate, fluoride, gramicidin, and azide on the formation of bacteriophage.
作者信息
PRICE W H
出版信息
J Gen Physiol. 1947 Nov 20;31(2):135-9. doi: 10.1085/jgp.31.2.135.
Abstract
- Iodoacetate, fluoride, and azide have been found to prevent the formation of phage and to inhibit the synthesis of ATP by Staphylococcus muscae. It is suggested that energy-rich phosphate is needed for the synthesis of phage. 2. Gramicidin prevented the formation of phage. 3. No differences were found between normal bacteria and phage-infected bacteria in the inorganic phosphate, adenosinetriphosphate, ribonucleic acid, and desoxyribonucleic acid content of the cells. 4. The mechanism of phage formation is discussed.
摘要
- 已发现碘乙酸盐、氟化物和叠氮化物可阻止噬菌体的形成，并抑制家蝇葡萄球菌合成三磷酸腺苷（ATP）。有人提出，噬菌体的合成需要富含能量的磷酸盐。2. 短杆菌肽可阻止噬菌体的形成。3. 在细胞的无机磷酸盐、三磷酸腺苷、核糖核酸和脱氧核糖核酸含量方面，未发现正常细菌与噬菌体感染细菌之间存在差异。4. 对噬菌体形成的机制进行了讨论。
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