[No rearrangement of the breakpoint cluster region in two juvenile chronic myeloid leukemia].
作者信息
Nakamura H, Tokunaga S, Sadamori N, Tomonaga M, Ichimaru M, Kinoshita K, Yanai M, Tsuji Y, Shimizu S
机构信息
Department of Internal Medicine, Atomic Disease Institute, Nagasaki University School of Medicine.
出版信息
Rinsho Ketsueki. 1991 Jun;32(6):690-2.
PMID:1890747
Abstract
We performed cytogenetic studies and breakpoint cluster region (bcr) rearrangement analysis in two cases of juvenile chronic myeloid leukemia (JCML) which is special type of chronic myeloid leukemia (CML). Case 1 (8-month-old male) and case 2 (3-month-old female) showed clinical and hematologic manifestations similar to CML. Each of case 1 and 2 had normal karyotype and no bcr rearrangement. These findings suggest that JCML is a different heterogeneous disorder from that of adult CML.
摘要
Zotero 插件