de Villiers Slabbert H, Altini M
Department of Oral Pathology, University of the Witwatersrand, Johannesburg, South Africa.
Oral Surg Oral Med Oral Pathol. 1991 Jul;72(1):86-90. doi: 10.1016/0030-4220(91)90195-i.
The clinicopathologic features of 30 cases of peripheral odontogenic fibroma are reviewed. The age distribution is wide (11 to 76 years), and there is a slight predilection for males. The majority of the lesions (93%) occurred in blacks on the attached gingiva, and with equal frequency in the maxilla and mandible. Size varied between 1 and 3 cm in diameter. One case recurred after 14 months. Histologically, the lesions are nonencapsulated and poorly delineated. The amount of odontogenic epithelium varies considerably and consists usually of small islands or strands, although larger follicles are sometimes present. In one case the epithelial cells had a clear cytoplasm, whereas in another it was granular and eosinophilic. Origin from the surface oral mucosa can sometimes be seen. The connective tissue component is usually cellular, but collagenous, myxomatous, and mixed forms occur. Calcifications were present in 22 cases and consisted of tissue interpreted as either dentinoid, cementum, bone, or dystrophic calcific material.
回顾了30例外周性牙源性纤维瘤的临床病理特征。年龄分布广泛（11至76岁），男性略多。大多数病变（93%）发生于黑人的附着龈，在上颌和下颌出现的频率相同。直径在1至3厘米之间不等。1例在14个月后复发。组织学上，病变无包膜，边界不清。牙源性上皮的数量差异很大，通常由小岛状或条索状组成，不过有时也会出现较大的滤泡。1例上皮细胞胞质透明，而另1例则呈颗粒状且嗜酸性。有时可见起源于口腔黏膜表面。结缔组织成分通常为细胞性，但也有胶原性、黏液瘤性及混合性形式。22例存在钙化，钙化组织被解释为类牙本质、牙骨质、骨或营养不良性钙化物质。
