Auriol M, Chomette G, Wann A, Guilbert F
Service d'Anatomie pathologique, Hôpital de la Pitié, Paris.
Rev Stomatol Chir Maxillofac. 1991;92(3):155-9.
30 metastases of malignant tumors in jaws were retrospectively studied. They occurred more often in women than in men (17 F/13 H). In 21 cases, the primitive cancer was known and had been treated 1 to 4 years before. In the other cases (9), the bone metastasis led to the discovery of a latent tumor. Clinical signs and symptoms included swelling, pain, loosening of teeth, labio-mental anaesthesia and rarely pathologic fracture. Radiologically, all but two patients had radiolucent lesion. These metastases almost always involved the mandible (95% of cases) and in that bone, most often molar area and angle. Histologically, the majority of lesions were adenocarcinomas from breast (33%) and alimentary canal (stomach, colon). Epidermoid bronchial carcinomas were seen in 5 cases and malignant melanomas in 2 cases. Only one sarcoma of this series was arising from a liposarcoma of the thigh. In all but one patients, evolution was quickly lethal.
对30例颌骨恶性肿瘤转移病例进行了回顾性研究。女性发病比男性更常见（17例女性/13例男性）。21例患者已知原发癌，且在1至4年前已接受治疗。在其他9例病例中，骨转移导致发现潜在肿瘤。临床体征和症状包括肿胀、疼痛、牙齿松动、唇颏部麻木，很少出现病理性骨折。放射学检查显示，除2例患者外，所有患者均有透射性病变。这些转移瘤几乎总是累及下颌骨（95%的病例），在该骨中，最常累及磨牙区和下颌角。组织学检查显示，大多数病变为来自乳腺（33%）和消化道（胃、结肠）的腺癌。5例为表皮样支气管癌，2例为恶性黑色素瘤。该系列中只有1例肉瘤起源于大腿脂肪肉瘤。除1例患者外，所有患者病情进展迅速，均导致死亡。
