Egloff L, Studer M, Siebenmann R, Hirzel H, Rothlin M, Tartini R
HerZentrum Hirslanden, Zürich.
Schweiz Med Wochenschr. 1991 Jul 20;121(29):1062-7.
Between 1987 and 1990 we operated on 104 patients for mitral valve disease. If possible the valve was reconstructed according to CARPENTIER's technique: 8 of 28 stenotic, 43 of 57 regurgitant and 2 of 7 mixed lesions were repaired. Twelve patients underwent re-replacement of a previously inserted mitral prosthesis. Six patients died early (7.8% after replacement, 8% after isolated replacement, 3.7% after repair and 2% after isolated repair). Five of these six patients were in NYHA class IV preoperatively. Seven patients died late after a mean observation period of 18 months (5 after replacement, 1 after double valve replacement and 1 after repair and multiple coronary bypass surgery). Prognosis is best for patients whose valve can be repaired and who are not already in NYHA class IV. The postoperative NYHA class for surviving patients is excellent (1.3 in the replacement group and 1.2 after repair).
1987年至1990年间，我们对104例二尖瓣疾病患者实施了手术。如有可能，按照卡彭蒂埃技术对瓣膜进行重建：28例狭窄病变患者中有8例、57例反流病变患者中有43例以及7例混合病变患者中有2例接受了修复。12例患者接受了二尖瓣人工瓣膜的再次置换。6例患者早期死亡（置换术后7.8%，单纯置换术后8%，修复术后3.7%，单纯修复术后2%）。这6例患者中有5例术前处于纽约心脏协会（NYHA）心功能IV级。7例患者在平均18个月的观察期后晚期死亡（置换术后5例，双瓣置换术后1例，修复及多次冠状动脉搭桥术后1例）。对于瓣膜能够修复且术前未处于NYHA心功能IV级的患者，预后最佳。存活患者术后NYHA心功能分级极佳（置换组为1.3级，修复术后为1.2级）。
