[Stomach and duodenal lesions in patients with acute organophosphorus pesticide poisonings].

Gastric and duodenal mucosa changes were studied by means of fibrogastroduodenoscopy and targeted biopsy in 35 patients, 23 men and 12 women, aged 18 to 68 years, with acute poisoning with phosphororganic pesticides. In 33 of the patients the poisoning occurred through oral and in 2 patients through cutaneous route. 13 patients were with a light, 14--with a moderate and 8--with a severe form of poisoning. In 31 patients (88.57%) edema and hyperemia were found, in 15 patients single and in 8 p. multiple erosions and in 4 p. ulcers were found, but in the duodenum they were more rare. The microscopic examination of the biopsies revealed variable changes--from edema, through focal accumulation of siderophages and single inflammatory infiltrates up to a severe fibrino-suppurative-necrotic process. A direct correlation between the severity of the lesions and the severity of the poisoning was found.