Yokoyama O, Miyazaki K, Ishida T, Fujita Y, Miyazaki R, Watanabe K
Department of Urology, Fujita Memorial Hospital.
Hinyokika Kiyo. 1991 Jun;37(6):617-20.
Bilateral renal cell carcinoma developing in a 55-year-old male receiving long-term dialysis is reported. The patient, who had undergone maintenance hemodialysis for 12 years, was admitted in July, 1986 for the purpose of extensive examination of a right renal mass. CT scan and ultrasonography demonstrated an enlarged bilateral kidney associated with multiple cysts, containing a solid mass in the right upper pole. The patients underwent right nephrectomy under the diagnosis of right renal tumor. The solid tumor 4 x 3 cm in size revealed a grade 1 to 2 renal cell carcinoma pathologically. Two small tumors were recognized in other portions of the kidney. Multiple cysts of varying sizes, the largest 2 cm in diameter, replaced the renal parenchyma. The cyst walls frequently contained hyperplastic changes. The patient has been subsequently followed up for 2 years and 9 months and underwent left nephrectomy for suspected left renal tumor. The surface of the left kidney was covered by numerous cysts. The result of pathological examination was renal cell carcinoma, which was recognized in a total of 7 regions of the left kidney. The patient remains well on hemodialysis, with no evidence of recurrence or metastasis.
报告了一例在接受长期透析的55岁男性患者中发生的双侧肾细胞癌。该患者已接受维持性血液透析12年,于1986年7月因对右侧肾脏肿块进行全面检查而入院。CT扫描和超声检查显示双侧肾脏增大,伴有多个囊肿,右肾上极有一个实性肿块。患者在诊断为右肾肿瘤后接受了右肾切除术。大小为4×3 cm的实性肿瘤在病理上显示为1至2级肾细胞癌。在肾脏的其他部位发现了两个小肿瘤。大小不一的多个囊肿取代了肾实质,最大直径为2 cm。囊肿壁经常有增生性改变。该患者随后接受了2年9个月的随访,并因疑似左肾肿瘤接受了左肾切除术。左肾表面布满了囊肿。病理检查结果为肾细胞癌,在左肾总共7个区域被发现。患者在血液透析中情况良好,没有复发或转移的迹象。