Parvizi Javad, Azzam Khalid, Rothman Richard H
Rothman Institute of Orthopedics at Thomas Jefferson University, Philadelphia, PA 19107, USA.
J Arthroplasty. 2008 Oct;23(7 Suppl):2-5. doi: 10.1016/j.arth.2008.06.028.
The orthopedic community continues to face a challenge with regard to the prevention of thromboembolism after total joint arthroplasty. The first and foremost issue facing surgeons is how to select the best agent or modality that is effective in preventing the untoward consequences of thromboembolism without causing other complications that can have dire consequences. Other challenges include the uncertainty regarding the dose and duration of various agents, the value of mechanical prophylaxis alone, and the exact end points that should be used to measure the efficacy of prophylaxis. This article discusses some of the recent developments in prevention and management of thromboembolism after total joint arthroplasty, in particular highlighting the guidelines that were developed by American Academy of Orthopedic Surgeons.
在全关节置换术后预防血栓栓塞方面，骨科界仍面临挑战。外科医生面临的首要问题是如何选择最佳的药物或方式，既能有效预防血栓栓塞的不良后果，又不会引发其他可能产生严重后果的并发症。其他挑战包括各种药物的剂量和疗程的不确定性、单纯机械预防的价值，以及用于衡量预防效果的确切终点。本文讨论了全关节置换术后血栓栓塞预防和管理方面的一些最新进展，特别强调了美国骨科医师学会制定的指南。
