Kalichman Leonid, Li Ling, Kim David H, Guermazi Ali, Berkin Valery, O'Donnell Christopher J, Hoffmann Udo, Cole Rob, Hunter David J
Boston University School of Medicine, Boston, MA, USA.
Spine (Phila Pa 1976). 2008 Nov 1;33(23):2560-5. doi: 10.1097/BRS.0b013e318184ef95.
Cross-sectional study.
To evaluate the association between lumbar spine facet joint osteoarthritis (FJ OA) identified by multidetector computed tomography (CT) and low back pain (LBP) in the community-based Framingham Heart Study.
The association between lumbar FJ OA and LBP remains unclear.
This study was an ancillary project to the Framingham Heart Study. A sample of 3529 participants of the Framingham Heart Study aged 40 to 80 underwent multidetector CT imaging to assess aortic calcification. One hundred eighty-eight individuals were consecutively enrolled in this ancillary study to assess radiographic features associated with LBP. LBP in the preceding 12 months was evaluated using a self-report questionnaire. FJ OA was evaluated on CT scans using a 4-grade scale. The association between FJ OA and LBP was examined used multiple logistic regression models, while adjusting for gender, age, and BMI.
CT imaging revealed a high prevalence of FJ OA (59.6% of males and 66.7% of females). Prevalence of FJ OA increases with age. By decade, FJ OA was present in 24.0% of <40-years-olds, 44.7% of 40- to 49-years-olds, 74.2% of 50- to 59-years-olds, 89.2% of 60- to 69-year-olds, and 69.2% of >70-years-olds. By spinal level the prevalence of FJ OA was: 15.1% at L2-L3, 30.6% at L3-L4, 45.1% at L4-L5, and 38.2% at L5-S1. In this community-based population, individuals with FJ OA at any spinal level showed no association with LBP.
There is a high prevalence of FJ OA in the community. Prevalence of FJ OA increases with age with the highest prevalence at the L4-L5 spinal level. At low spinal levels women have a higher prevalence of lumbar FJ OA than men. In the present study, we failed to find an association between FJ OA, identified by multidetector CT, at any spinal level and LBP in a community-based study population.
横断面研究。
在基于社区的弗雷明汉心脏研究中，评估通过多排螺旋计算机断层扫描（CT）确定的腰椎小关节骨关节炎（FJ OA）与腰痛（LBP）之间的关联。
腰椎FJ OA与LBP之间的关联仍不明确。
本研究是弗雷明汉心脏研究的一个辅助项目。对3529名年龄在40至80岁的弗雷明汉心脏研究参与者进行多排螺旋CT成像，以评估主动脉钙化情况。188名个体连续纳入该辅助研究，以评估与LBP相关的影像学特征。使用自我报告问卷评估前12个月内的LBP情况。在CT扫描上使用4级量表评估FJ OA。使用多元逻辑回归模型检查FJ OA与LBP之间的关联，同时对性别、年龄和体重指数进行校正。
CT成像显示FJ OA的患病率很高（男性为59.6%，女性为66.7%）。FJ OA的患病率随年龄增加而升高。按十年划分，FJ OA在<40岁人群中的患病率为24.0%，40至49岁人群中的患病率为44.7%，50至59岁人群中的患病率为74.2%，60至69岁人群中的患病率为89.2%，>70岁人群中的患病率为69.2%。按脊柱节段划分，FJ OA的患病率分别为：L2-L3节段为15.1%，L3-L4节段为30.6%，L4-L5节段为45.1%，L5-S1节段为38.2%。在这个基于社区的人群中，任何脊柱节段存在FJ OA的个体与LBP均无关联。
社区中FJ OA的患病率很高。FJ OA的患病率随年龄增加而升高，在L4-L5脊柱节段患病率最高。在较低脊柱节段，女性腰椎FJ OA的患病率高于男性。在本研究中，我们未能在基于社区的研究人群中发现通过多排螺旋CT确定的任何脊柱节段的FJ OA与LBP之间存在关联。
