Eubanks Jason David, Lee Michael J, Cassinelli Ezequiel, Ahn Nicholas U
Department of Orthopaedics, Case Western Reserve University, Cleveland, OH 44106, USA.
Spine (Phila Pa 1976). 2007 Sep 1;32(19):2058-62. doi: 10.1097/BRS.0b013e318145a3a9.
An anatomic, epidemiologic study of facet arthrosis in cadaveric lumbar spines.
To define the prevalence of lumbar facet arthrosis in a large population sample and to examine its association with age, sex, and race.
Arthrosis of lumbar facet joints is a common radiographic finding and has been linked to low back pain. However, no population studies have specifically defined the prevalence of facet arthrosis in the lumbar spine in relation to age, sex, and race.
A total of 647 cadaveric lumbar spines were examined by a single examiner for evidence of lumbar facet arthrosis. Information on race, age, and sex were collected. Arthrosis at each facet was graded from 0 to 4 on a continuum from no arthritis to complete ankylosis.
Facet arthrosis was present in 53% (L1-L2), 66% (L2-L3), 72% (L3-L4), 79% (L4-L5), and 59% (L5-S1). By decade, facet arthrosis was present in 57% of 20- to 29-year-olds, 82% of 30- to 39-year-olds, 93% of 40- to 49-year-olds, 97% in 50- to 59-year-olds, and 100% in those >60 years old. Fisher exact test and t test demonstrated that men had a greater prevalence and degree of facet arthrosis than women at all lumbar levels (P < 0.001). The lumbar level with the highest prevalence and degree of arthrosis was the L4-L5 level, as compared with each of the other levels (P < 0.001). There was no difference in arthrosis between right versus left facet joints (P > 0.5).
Facet arthrosis is a universal finding in the human lumbar spine. Evidence of arthrosis begins early, with more than one half of adults younger than 30 years demonstrating arthritic changes in the facets. The most common arthritic level appears to be L4-L5. Men have a higher prevalence and degree of facet arthrosis than women.
对尸体腰椎小关节骨关节炎进行解剖学、流行病学研究。
确定大样本人群中腰椎小关节骨关节炎的患病率，并研究其与年龄、性别和种族的关系。
腰椎小关节骨关节炎是常见的影像学表现，且与腰痛有关。然而，尚无人群研究具体确定腰椎小关节骨关节炎与年龄、性别和种族相关的患病率。
由一名检查者对647具尸体腰椎进行检查，以寻找腰椎小关节骨关节炎的证据。收集种族、年龄和性别的信息。每个小关节的骨关节炎从无关节炎到完全强直分为0至4级。
小关节骨关节炎的发生率在L1-L2为53%，L2-L3为66%，L3-L4为72%，L4-L5为79%，L5-S1为59%。按十年划分，20至29岁人群中57%有小关节骨关节炎，30至39岁人群中82%有，40至49岁人群中93%有，50至59岁人群中97%有，60岁以上人群中100%有。Fisher精确检验和t检验表明，在所有腰椎节段，男性小关节骨关节炎的患病率和程度均高于女性（P < 0.001）。与其他各节段相比，骨关节炎患病率和程度最高的腰椎节段是L4-L5节段（P < 0.001）。左右小关节之间的骨关节炎无差异（P > 0.5）。
小关节骨关节炎在人类腰椎中普遍存在。骨关节炎的证据出现较早，30岁以下的成年人中超过一半的人小关节有骨关节炎改变。最常见的骨关节炎节段似乎是L4-L5。男性小关节骨关节炎的患病率和程度高于女性。
