Evans Jessica, Chen Yue
Department of Epidemiology and Community Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada.
Inhal Toxicol. 2009 Feb;21(3):244-9. doi: 10.1080/08958370802409567.
This study aimed to determine the association between home and vehicle exposure to environmental tobacco smoke (ETS), and chronic bronchitis based on data from 64,961 non-smokers aged 12 years and older who participated in the 2005 Canadian Community Health Survey (CCHS). The proportion of respondents who reported ETS exposure in the home and vehicle was 9.0% and 8.4% respectively. The prevalence of self-reported doctor diagnosed chronic bronchitis was 1.5%. When considered separately, home and vehicle ETS were both significantly associated with chronic bronchitis in children and adolescents aged 12-19 years, with adjusted odds ratios of 2.30 (95% CI 1.46-3.63) and 2.25 (95% CI 1.42-3.58), respectively. Neither home, nor vehicle ETS exposure was significantly associated with chronic bronchitis in age groups greater than 19 years. When home and vehicle ETS exposure were considered together, and sex, age, allergies, asthma, marital status, level of education, and race where controlled for, home ETS exposure was not a significant predictor of chronic bronchitis (P = 0.296), while vehicle ETS was. The correlation between exposure variables was fair, with a kappa coefficient of 0.40 (P < 0.0001). Females, older age groups, non-white individuals, asthmatic patients, as well as individuals with allergies, no high school diploma, and those who were previously married had higher odds of chronic bronchitis. In conclusion, vehicle exposure to ETS was significantly associated with chronic bronchitis, and children and adolescents exposed to ETS were more susceptible to the disease.
本研究旨在根据参与2005年加拿大社区健康调查(CCHS)的64961名12岁及以上非吸烟者的数据,确定家庭和车辆环境烟草烟雾(ETS)暴露与慢性支气管炎之间的关联。报告在家中和车辆中暴露于ETS的受访者比例分别为9.0%和8.4%。自我报告经医生诊断为慢性支气管炎的患病率为1.5%。单独考虑时,家中和车辆中的ETS暴露均与12 - 19岁儿童和青少年的慢性支气管炎显著相关,调整后的优势比分别为2.30(95%CI 1.46 - 3.63)和2.25(95%CI 1.42 - 3.58)。在19岁以上年龄组中,家中和车辆中的ETS暴露均与慢性支气管炎无显著关联。当同时考虑家中和车辆中的ETS暴露,并对性别、年龄、过敏、哮喘、婚姻状况、教育水平和种族进行控制时,家中的ETS暴露不是慢性支气管炎的显著预测因素(P = 0.296),而车辆中的ETS暴露是。暴露变量之间的相关性一般,kappa系数为0.40(P < 0.0001)。女性、年龄较大的年龄组、非白人个体、哮喘患者以及有过敏史、没有高中文凭和曾结婚的个体患慢性支气管炎的几率更高。总之,车辆中暴露于ETS与慢性支气管炎显著相关,暴露于ETS的儿童和青少年更容易患该病。