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[腹膜癌病行术中热灌注化疗(HIPEC)的腹膜切除术选择标准]

[Selection criteria for peritonectomy with hyperthermic intraoperative chemotherapy (HIPEC) in peritoneal carcinomatosis].

作者信息

Königsrainer I, Aschoff P, Zieker D, Beckert S, Glatzle J, Pfannenberg C, Miller S, Hartmann J T, Schroeder T H, Brücher B L D M, Königsrainer A

机构信息

Klinik für Allgemeine, Viszeral- und Transplantationschirurgie, Tübingen.

出版信息

Zentralbl Chir. 2008 Sep;133(5):468-72. doi: 10.1055/s-2008-1076973. Epub 2008 Oct 15.

Abstract

BACKGROUND

Cytoreductive peritonectomy with hyperthermic intraoperative chemotherapy (HIPEC) is an established therapy for patients with gastrointestinal, gynaecological metastasised peritoneal carcinomatosis as well as primary peritoneal carcinomatous tumours.

METHODS

On the basis of a literature review and our personal experience, selection criteria for peritonectomy are discussed.

RESULTS

Computed tomography (CT) scans and diagnostic laparoscopy are not sufficient for the diagnosis of peritoneal carcinomatosis. The combination of fluorodeoxyglucose positron emission tomography (FDG-PET) and CT seems to be the most reliable diagnostic imaging method. In our institution, all patients undergo PET / CT prior to peritonectomy.

CONCLUSION

The PET / CT scan may play an important role in forecasting the operability of patients with peritoneal carcinomatosis.

摘要

背景

细胞减灭性腹膜切除术联合术中热灌注化疗(HIPEC)是治疗胃肠道、妇科转移性腹膜癌以及原发性腹膜癌肿瘤患者的既定疗法。

方法

基于文献综述和我们的个人经验,讨论了腹膜切除术的选择标准。

结果

计算机断层扫描(CT)和诊断性腹腔镜检查不足以诊断腹膜癌。氟脱氧葡萄糖正电子发射断层扫描(FDG-PET)和CT的联合似乎是最可靠的诊断成像方法。在我们机构,所有患者在腹膜切除术前行PET/CT检查。

结论

PET/CT扫描在预测腹膜癌患者的可手术性方面可能发挥重要作用。

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