Sato K, Higaki Y, Sakaguchi S, Hirano M, Tanimura A, Sasaguri Y
Department of Otolaryngology-Head and Neck Surgery, Kurume University School of Medicine, Japan.
Auris Nasus Larynx. 1991;18(1):39-53. doi: 10.1016/s0385-8146(12)80249-5.
Carcinoid tumor of the larynx is a rare neoplasm. Two cases of laryngeal carcinoid tumor are reported and the relevant literature is reviewed. One patient was an 82-year-old male who complained of odynophagia. The tumor was located on the left arytenoid and neck metastasis were present when he died 3 years after surgery. The other patient was an 82-year-old male who complained of hoarseness. His tumor was located in the left ventricle. Bone metastasis was detected one month after surgery and he died of distant metastasis two months following surgery. A review of the literature showed that carcinoid tumors of the larynx are aggressive and malignant, with distant metastasis being the most common cause of death. This tumor is unresponsive to radiotherapy and chemotherapy, so adequate surgical excision remains the only effective treatment.
喉类癌是一种罕见的肿瘤。本文报告了2例喉类癌病例并复习相关文献。1例患者为82岁男性,主诉吞咽疼痛。肿瘤位于左杓状软骨,术后3年死亡时出现颈部转移。另1例患者为82岁男性,主诉声音嘶哑。其肿瘤位于左心室。术后1个月检测到骨转移,术后2个月死于远处转移。文献复习显示,喉类癌具有侵袭性和恶性,远处转移是最常见的死亡原因。该肿瘤对放疗和化疗均无反应,因此充分的手术切除仍然是唯一有效的治疗方法。