Gapany-Gapanavicius B, Kenan S
Ann Otol Rhinol Laryngol. 1981 Jan-Feb;90(1 Pt 1):42-7. doi: 10.1177/000348948109000111.
Primary carcinoid of the larynx is an unusual neoplasm. Only one case could be traced in the literature so far. Another case, a 55-year-old male patient, is presented and discussed. The tumor proved to be malignant, showing histological, histochemical and electron microscopical characteristics of a carcinoid. Initially there was a striking discrepancy between the scanty findings in the larynx and the wide metastatic spread of the tumor into the cervical lymph nodes along the internal jugular vein, and the progression of the process was markedly slower than that of laryngeal carcinoma. Despite the massive dose of radiotherapy that had been administered after radical neck dissection in an attempt to preserve the larynx, the tumor continued to expand, infiltrating the laryngeal tissues and causing stenosis that necessitated total laryngectomy, thus again proving that the treatment of choice in laryngeal carcinoid should be wide surgical excision.
原发性喉类癌是一种罕见的肿瘤。迄今为止，文献中仅能查到一例。本文报告并讨论了另一例病例，患者为一名55岁男性。肿瘤被证实为恶性，具有类癌的组织学、组织化学和电子显微镜特征。最初，喉部的微小病变与肿瘤沿颈内静脉广泛转移至颈部淋巴结的情况存在显著差异，且病程进展明显慢于喉癌。尽管在根治性颈清扫术后给予了大剂量放疗以试图保留喉部，但肿瘤仍继续扩大，浸润喉部组织并导致狭窄，最终不得不进行全喉切除术，这再次证明喉类癌的首选治疗方法应为广泛的手术切除。
