Jovancević Ljiljana, Dankuc Dragan
Klinicki centar Vojvodine, Klinika za bolesti uva, grla i nosa, 21000 Novi Sad, Hajduk Veljkova 1-7.
Med Pregl. 2008;61 Suppl 2:41-6.
Acute poisonings with corrosive substances make 15-20% of all acute poisonings in our country. They are on the second place, after drug poisonings, which are far more often. After the ingestion of corrosives, corrosive lesions of the gastrointestinal tract appear. The oesophagus has lesions mostly in cases of ingestion of alkali, and the stomach (gaster) is damaged when an acid is ingested The first steps in the management of the patients having ingested a corrosive substance are to stabilise all vital parameters of the patient (reanimation) and to dilute the substance. The dilution can be done within 60 minutes, with water or milk. After the stabilisation of all vital parameters, the further treatment should start, meaning diagnostics and therapeutic measures. The best diagnostic procedure to determine the presence and severity of corrosive oesophageal lesions is oesophagoscopy. Basic therapeutic principles in the management of patients after corrosive substance ingestion must be applied. According to these principles, it is contraindicated to induce vomiting, diarrhoea and do corrosive substance neutralisation or gastric lavage. Charcoal has no effect, and is not indicated. It is important to identify the kind and quantity of ingested substance, as well as to withhold all oral feedings, and to assess fluid and electrolyte balance carefully and to watch for development of complications. This paper presents the complete treatment protocol of ENT Clinic, Clinical Center of Vojvodina, Serbia. This protocol has been in use since the year 2000 and the results are excellent.
腐蚀性物质引起的急性中毒占我国所有急性中毒病例的15% - 20%。它们位居第二,仅次于更为常见的药物中毒。摄入腐蚀性物质后,胃肠道会出现腐蚀性损伤。摄入碱性物质时,食管大多会出现损伤,而摄入酸性物质时,胃会受到损害。对于摄入腐蚀性物质的患者,首要处理步骤是稳定患者的所有生命体征(复苏)并稀释该物质。可在60分钟内用水或牛奶进行稀释。在所有生命体征稳定后,应开始进一步治疗,即诊断和采取治疗措施。确定腐蚀性食管损伤的存在和严重程度的最佳诊断方法是食管镜检查。必须应用腐蚀性物质摄入后患者管理的基本治疗原则。根据这些原则,禁忌催吐、导泻以及进行腐蚀性物质中和或洗胃。活性炭无效,不建议使用。确定摄入物质的种类和数量、停止所有经口喂食、仔细评估液体和电解质平衡以及密切关注并发症的发生非常重要。本文介绍了塞尔维亚伏伊伏丁那临床中心耳鼻喉科诊所的完整治疗方案。该方案自2000年起开始使用,效果极佳。