Al-Khatib Sana M, Sanders Gillian D, Carlson Mark, Cicic Aida, Curtis Anne, Fonarow Gregg C, Groeneveld Peter W, Hayes David, Heidenreich Paul, Mark Daniel, Peterson Eric, Prystowsky Eric N, Sager Philip, Salive Marcel E, Thomas Kevin, Yancy Clyde W, Zareba Wojciech, Zipes Douglas
The Duke Clinical Research Institute, Durham, NC 27715, USA.
Am Heart J. 2008 Oct;156(4):613-22. doi: 10.1016/j.ahj.2008.05.027. Epub 2008 Jul 26.
Because the burden of sudden cardiac death (SCD) is substantial, it is important to use all guideline-driven therapies to prevent SCD. Among those therapies is the implantable cardioverter defibrillator (ICD). When indicated, ICD use is beneficial and cost-effective. Unfortunately, studies suggest that most patients who have indications for this therapy for primary or secondary prevention of SCD are not receiving it. To explore potential reasons for this underuse and to propose potential facilitators for ICD dissemination, the Duke Center for the Prevention of SCD at the Duke Clinical Research Institute (Durham, NC) organized a think tank meeting of experts on this issue. The meeting took place on December 12 and 13, 2007, and it included representatives of clinical cardiology, cardiac electrophysiology, general internal medicine, economics, health policy, the US Food and Drug Administration, the Centers for Medicare and Medicaid Services, the Agency for Health care Research and Quality, and the device and pharmaceutical industry. Although the meeting was funded by industry participants, this article summarizing the presentations and discussions that occurred at the meeting presents the expert opinion of the authors.
由于心源性猝死(SCD)的负担沉重,采用所有遵循指南的疗法来预防SCD很重要。这些疗法中包括植入式心律转复除颤器(ICD)。在有指征时,使用ICD是有益且具有成本效益的。不幸的是,研究表明,大多数有该疗法用于一级或二级预防SCD指征的患者并未接受该治疗。为探究这种使用不足的潜在原因并提出ICD推广的潜在促进因素,杜克临床研究所(北卡罗来纳州达勒姆)的杜克SCD预防中心就这一问题组织了一次专家智囊团会议。会议于2007年12月12日和13日举行,与会人员包括临床心脏病学、心脏电生理学、普通内科、经济学、卫生政策、美国食品药品监督管理局、医疗保险和医疗补助服务中心、医疗保健研究与质量局以及设备和制药行业的代表。尽管会议由行业参与者资助,但本文总结了会议上的发言和讨论内容,呈现了作者们的专家意见。