Rinaggio Joseph, Hameed Meera, Baredes Soly
Department of Diagnostic Sciences, University of Medicine and Dentistry of New Jersey, New Jersey Dental School, Newark, NJ 07103-2400, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Dec;106(6):861-5. doi: 10.1016/j.tripleo.2008.08.019. Epub 2008 Oct 16.
Mucosal melanomas are uncommon in comparison to their counterpart on the skin, accounting for approximately 1% of all such tumors. The majority of mucosal melanomas arise within the head and neck region. Osteocartilaginous differentiation in these tumors is a rare phenomenon and can pose diagnostic challenges. Herein we report a case of melanoma with cartilaginous differentiation originating in the nasal cavity of a 76-year-old male, presenting dramatically as a large mass projecting well beyond the vestibule of the right naris. To our knowledge, this case represents the fifth example of a melanoma with bone and/or cartilage differentiation to arise in the head and neck region, and the third to be reported in the nasal cavity.
与皮肤黑色素瘤相比，黏膜黑色素瘤并不常见，约占所有此类肿瘤的1%。大多数黏膜黑色素瘤发生在头颈部区域。这些肿瘤中的骨软骨分化是一种罕见现象，可能带来诊断挑战。在此，我们报告一例起源于一名76岁男性鼻腔的具有软骨分化的黑色素瘤病例，该肿瘤显著表现为一个巨大肿块，突出于右鼻孔前庭之外。据我们所知，该病例是头颈部区域出现的具有骨和/或软骨分化的黑色素瘤的第五个病例，也是鼻腔中报告的第三个病例。
