Tappe Dennis, Weise David, Ziegler Uwe, Müller Andreas, Müllges Wolfgang, Stich August
Department of Tropical Medicine, Medical Mission Hospital, Salvatorstrasse 7, 97067 Würzburg, Germany.
German Consiliary Laboratory for Echinococcosis, Institute of Hygiene and Microbiology, University of Würzburg, Josef-Schneider-Strasse 2, 97080 Würzburg, Germany.
J Med Microbiol. 2008 Nov;57(Pt 11):1420-1423. doi: 10.1099/jmm.0.2008/002816-0.
Alveolar echinococcosis (AE) of the liver with cerebral and pulmonary metastasis was diagnosed in a Tibetan monk who initially presented with severe headache to an emergency department in Germany. Multiple lesions with perifocal oedema and severe compression of the third ventricle were seen with computed tomography (CT) of the brain. Glioma or cerebral metastasis of a hitherto undiagnosed abdominal or pulmonary malignancy was suspected. CT scans of the lung and liver demonstrated further tumorous masses. Magnetic resonance imaging of the brain revealed the cystic nature of the cerebral lesions and the patient had a highly positive serology for AE. The echinococcal aetiology of the brain lesions was confirmed by PCR for this refugee from an area where two disease entities, AE and cystic echinococcosis, are hyperendemic.
一名藏族僧侣被诊断为肝脏泡型包虫病(AE)伴脑和肺转移,他最初因严重头痛前往德国一家急诊科就诊。脑部计算机断层扫描(CT)显示多个病灶伴有灶周水肿,第三脑室严重受压。怀疑为胶质瘤或此前未确诊的腹部或肺部恶性肿瘤的脑转移。肺部和肝脏的CT扫描显示还有其他肿瘤性肿块。脑部磁共振成像显示脑部病变为囊性,该患者AE血清学检测呈强阳性。通过聚合酶链反应(PCR)证实了该来自AE和囊型包虫病这两种疾病高度流行地区的难民脑部病变的棘球蚴病因。