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[采用基于意大利不同地区电子健康数据的标准算法估算急性心肌梗死发病率]

[Acute myocardial infarction incidence estimated using a standard algorithm based on electronic health data in different areas of Italy].

作者信息

Barchielli Alessandro, Balzi Daniela, Bruni Antonella, Canova Cristina, Cesaroni Giulia, Gnavi Roberto, Picariello Roberta, Inio Andrea, Protti Mariangela, Romanelli Anna, Tessari Roberta, Vigotti Maria Angela, Simonato Lorenzo

机构信息

Unità di epidemiologia, Azienda sanitaria 10, Firenze.

出版信息

Epidemiol Prev. 2008 May-Jun;32(3 Suppl):30-7.

Abstract

AIM

to define and implement an algorithm, based on current databases, in order to estimate acute myocardial infarction (AMI) incidence in six Italian areas.

SETTING

Local Health Units of Firenze and Venezia, and the municipalities of Pisa, Roma, Taranto, and Torino.

PARTICIPANTS

residents in the above mentioned six areas in the period 2002-2004, for a total of about 4,447,000 subjects (30th June 2003).

METHODS

acute myocardial infarction incident cases were identified through hospitalization databases and causes of death. Hospital discharges (excluding outpatient discharges) with ICD9-CM code 410* as primary discharge diagnosis, or as secondary diagnosis when associated with selected codes suggestive of ischemic symptoms in primary diagnosis, and deaths with the ICD9-CM code 410* as underlying cause were selected. Patients without a previous hospitalization for ICD9-CM codes 410* and 412* during the previous 60 months were considered as incident cases. Crude, age-specific and age-standardized incidence rates (standard: total Italian population at the 2001 census) were calculated. A number of data quality indicators were also evaluated.

RESULTS

age-standardized incidence rates show different levels of incidence in the areas included in the study. Both for males and females, higher incidence is observed in Rome and Turin (males: respectively 260.5 and 260.2 cases/100,000; females: 105.6 cases/100,000 in both areas). The lowest incidence is observed in Taranto (males: 219.5 cases/100,000; females: 87.0 cases/100,000). Quality indicators suggest a good comparability of incidence estimates among the studied areas. In particular, in both genders, the differences observed in the incidence rates are consistent with the differences of current AMI mortality rates.

CONCLUSIONS

although limitations in data comparability among the studied areas and in the quality of disease coding cannot be completely excluded, results suggest that the algorithm we used provides estimates of AMI incidence rates comparable among the studied areas. Only a validation study with standardized criteria will make it possible to more closely evaluate the diagnostic quality and comparability of AMI cases identified through this algorithm.

摘要

目的

基于现有数据库定义并实施一种算法,以估算意大利六个地区的急性心肌梗死(AMI)发病率。

地点

佛罗伦萨和威尼斯的地方卫生单位,以及比萨、罗马、塔兰托和都灵市。

参与者

2002年至2004年期间上述六个地区的居民,共计约444.7万人(2003年6月30日)。

方法

通过住院数据库和死亡原因确定急性心肌梗死发病病例。选择国际疾病分类第九版临床修订本(ICD9-CM)编码410作为主要出院诊断的住院病例(不包括门诊出院病例),或在主要诊断中与提示缺血症状的选定编码相关联时作为次要诊断的病例,以及以ICD9-CM编码410作为根本死因的死亡病例。在过去60个月内未曾因ICD9-CM编码410和412住院的患者被视为发病病例。计算粗发病率、年龄别发病率和年龄标准化发病率(标准:2001年人口普查时的意大利总人口)。还评估了一些数据质量指标。

结果

年龄标准化发病率显示研究中各地区的发病率水平不同。无论男性还是女性,罗马和都灵的发病率较高(男性:分别为260.5例/10万和260.2例/10万;女性:两个地区均为105.6例/10万)。塔兰托的发病率最低(男性:219.5例/10万;女性:87.0例/10万)。质量指标表明研究地区之间发病率估计值具有良好的可比性。特别是,无论男性还是女性,发病率的差异与当前AMI死亡率的差异一致。

结论

尽管不能完全排除研究地区之间数据可比性和疾病编码质量方面的局限性,但结果表明我们使用的算法能够提供研究地区之间可比的AMI发病率估计值。只有通过标准化标准进行的验证研究才能更密切地评估通过该算法识别的AMI病例的诊断质量和可比性。

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