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端侧神经修复:文献综述与临床指征

End-to-side nerve repair: review of the literature and clinical indications.

作者信息

Dvali Linda T, Myckatyn Terence M

机构信息

Division of Plastic and Reconstructive Surgery, University of Toronto, University Health Network, Toronto Western Division, 2-400, 399 Bathurst Street, Toronto, Ontario, M5T 2S8, Canada.

出版信息

Hand Clin. 2008 Nov;24(4):455-60, vii. doi: 10.1016/j.hcl.2008.04.006.

DOI:10.1016/j.hcl.2008.04.006
PMID:18928893
Abstract

End-to-side (ETS) nerve repair, in which the distal stump of a transected nerve is coapted to the side of an uninjured donor nerve, has been suggested as a technique for repair of peripheral nerve injuries where the proximal nerve stump is unavailable or a significant nerve gap exists. Full review of the ETS literature suggests that sensory recovery after ETS repair results in some, but not robust, regeneration. Sensory axons will sprout without deliberate injury. However, motor axons only regenerate after deliberate nerve injury. Experimental and clinical experience with ETS neurorrhaphy has rendered mixed results. Continued research into ETS nerve repair is warranted. ETS techniques should not yet replace safer and more reliable techniques of nerve repair except when some, but not good, sensory recovery is appropriate and a deliberate injury to the donor motor nerve is made.

摘要

端侧(ETS)神经修复是将横断神经的远侧残端与未受损的供体神经的侧面吻合,有人提出将其作为一种修复周围神经损伤的技术,适用于近端神经残端无法获得或存在明显神经间隙的情况。对ETS文献的全面回顾表明,ETS修复后的感觉恢复会产生一定程度的再生,但并不强劲。感觉轴突在没有故意损伤的情况下也会发芽。然而,运动轴突只有在故意神经损伤后才会再生。ETS神经缝合术的实验和临床经验结果不一。有必要继续对ETS神经修复进行研究。除非某些(但并非良好的)感觉恢复是合适的,并且对供体运动神经进行了故意损伤,否则ETS技术不应取代更安全、更可靠的神经修复技术。

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End-to-Side vs. Free Graft Nerve Reconstruction-Experimental Study on Rats.端侧吻合与游离神经移植重建术的比较-大鼠的实验研究。
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The reasons for end-to-side coaptation: how does lateral axon sprouting work?端侧吻合的原因:轴突侧支发芽是如何起作用的?
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Comparison of Peripheral Nerve Regeneration with Side-to-side, End-to-side, and End-to-end Repairs: An Experimental Study.周围神经侧侧、端侧和端端修复后再生情况的比较:一项实验研究
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