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小儿脐下小手术的骶管麻醉:左旋布比卡因单用与左旋布比卡因加舒芬太尼的比较

Caudal anesthesia for minor subumbilical pediatric surgery: a comparison of levobupivacaine alone and levobupivacaine plus sufentanil.

作者信息

Erol Atilla, Tavlan Aybars, Tuncer Sema, Topal Ahmet, Yurtcu Müslim, Reisli Ruhiye, Otelcioglu Seref

机构信息

Department of Anaesthesiology and Intensive Care, University of Selcuk of Meram Medicine Faculty, Konya, Turkey.

出版信息

J Clin Anesth. 2008 Sep;20(6):442-6. doi: 10.1016/j.jclinane.2008.04.010.

DOI:10.1016/j.jclinane.2008.04.010
PMID:18929285
Abstract

STUDY OBJECTIVES

To compare the postoperative analgesic efficacy and duration of analgesia after caudal levobupivacaine 0.20% with and without the addition of sufentanil 0.5 microg kg(-1).

DESIGN

Prospective, randomized study.

SETTING

University teaching hospital.

PATIENTS

40 ASA physical status I pediatric patients, aged one to 7 years, who were scheduled for elective minor subumbilical surgery.

INTERVENTIONS

Patients were divided into two groups to receive either a single caudal injection of one mL kg(-1) levobupivacaine 0.20% (Group L) or levobupivacaine 0.20% plus sufentanil 0.5 microg kg(-1) (Group LS).

MEASUREMENTS

Analgesia (Children and Infants Postoperative Pain Scale score), motor block (Motor Blockade Scoring), and side effects were assessed at predetermined time points during the first 24 postoperative hours.

MAIN RESULTS

The Children and Infants Postoperative Pain Scale scoring at the first hour was significantly lower in Group LS than in Group L. No significant differences were found between the two groups for pain scores at two, three, 4, 5, 6, 9, 12, and 24 hours. Degree of motor block was comparable between the two groups.

CONCLUSION

The effect of adding sufentanil to caudal levobupivacaine on postoperative pain scores is brief after elective minor subumbilical surgery in children.

摘要

研究目的

比较0.20%左旋布比卡因骶管阻滞单独使用与联合0.5μg/kg舒芬太尼使用时的术后镇痛效果及镇痛持续时间。

设计

前瞻性随机研究。

地点

大学教学医院。

患者

40例年龄1至7岁、ASA身体状况分级为I级、计划行择期脐下小手术的儿科患者。

干预措施

患者被分为两组,分别接受单次骶管注射1mL/kg 0.20%左旋布比卡因(L组)或0.20%左旋布比卡因加0.5μg/kg舒芬太尼(LS组)。

测量指标

在术后24小时内的预定时间点评估镇痛效果(儿童和婴儿术后疼痛量表评分)、运动阻滞(运动阻滞评分)及副作用。

主要结果

LS组术后第1小时的儿童和婴儿术后疼痛量表评分显著低于L组。两组在术后2、3、4、5、6、9、12和24小时的疼痛评分无显著差异。两组运动阻滞程度相当。

结论

在儿童择期脐下小手术后,骶管注射左旋布比卡因时添加舒芬太尼对术后疼痛评分的影响短暂。

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