开发一种使用液相色谱-串联质谱法测定水、沉积物和土壤中阿维菌素的分析方法。
Development of an analytical method to determine avermectins in water, sediments and soils using liquid chromatography-tandem mass spectrometry.
作者信息
Krogh K A, Björklund E, Loeffler D, Fink G, Halling-Sørensen B, Ternes T A
机构信息
Section of Toxicology and Environmental Chemistry, Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Science, Copenhagen University, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
出版信息
J Chromatogr A. 2008 Nov 21;1211(1-2):60-9. doi: 10.1016/j.chroma.2008.09.081. Epub 2008 Oct 1.
A comprehensive analytical multi-residue method has been developed for the determination of seven avermectins (abamectin, doramectin, ivermectin, emamectin benzoate, eprinomectin, moxidectin and selamectin) in surface water, sediment and soil samples. Solid samples were extracted applying pressurised liquid extraction followed by a solid-phase extraction (SPE) clean-up step. For aqueous samples, extraction was done utilising only SPE. All compounds were measured using liquid chromatography coupled to tandem mass spectrometry using atmospheric pressure chemical ionisation. The recoveries were 38-67% (relative standard deviation: 9-26%), 63-88% (16-23%) and 63-80% (9-15%) for spiked Rhine water, spiked sediment and spiked soil samples, respectively, and limit of quantifications were 2.5-14 ngl(-1) in water and 0.5-2.5 ngg(-1) in soil and sediment.
已开发出一种综合分析多残留方法，用于测定地表水、沉积物和土壤样品中的七种阿维菌素（阿维菌素、多拉菌素、伊维菌素、甲氨基阿维菌素苯甲酸盐、埃普利诺菌素、莫西菌素和塞拉菌素）。固体样品采用加压液体萃取，随后进行固相萃取（SPE）净化步骤。对于水样，仅使用SPE进行萃取。所有化合物均采用液相色谱-串联质谱联用，通过大气压化学电离进行测定。加标莱茵河水、加标沉积物和加标土壤样品的回收率分别为38-67%（相对标准偏差：9-26%）、63-88%（16-23%）和63-80%（9-15%），水中的定量限为2.5-14 ng l(-1)，土壤和沉积物中的定量限为0.5-2.5 ng g(-1)。
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