Diamantis A, Magiorkinis E, Androutsos G
Office for the Study of History of Hellenic Naval Medicine, Naval Hospital of Athens, Athens, Greece.
J Urol. 2008 Dec;180(6):2330-2; discussion 2322. doi: 10.1016/j.juro.2008.08.043. Epub 2008 Oct 18.
We present the evolution of ideas on the concept of proteinuria from antiquity through the 19th century.
We conducted a thorough study of texts, medical books and reports along with a review of the available literature in PubMed.
Observations on proteinuria date back nearly 2,500 years to the works of Hippocrates. In the 17th and 18th centuries physicians and clinical chemists, particularly Frederick Dekkers, Domenico Cotugno and Charles Wells, further increased the knowledge of proteinuria. Contrary to popular belief the first appearance of the term albuminuria in print should be attributed to Martin Solon in 1837.
Observations on proteinuria span approximately 2,500 years. The work of physicians during the 17th and 18th centuries led to its establishment as a separate clinical entity associated with renal disease.
我们展示了从古代到19世纪关于蛋白尿概念的思想演变。
我们对文本、医学书籍和报告进行了全面研究，并查阅了PubMed上的现有文献。
对蛋白尿的观察可追溯到近2500年前希波克拉底的著作。在17和18世纪，医生和临床化学家，特别是弗雷德里克·德克斯、多梅尼科·科图尼奥和查尔斯·韦尔斯，进一步增加了对蛋白尿的认识。与普遍看法相反，“白蛋白尿”一词首次在印刷品中出现应归功于1837年的马丁·索伦。
对蛋白尿的观察跨越了大约2500年。17和18世纪医生的工作使其成为与肾脏疾病相关的一个独立临床实体。
