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眼科中的飞秒激光。

Femtosecond lasers in ophthalmology.

作者信息

Soong H Kaz, Malta João Baptista

机构信息

Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.

出版信息

Am J Ophthalmol. 2009 Feb;147(2):189-197.e2. doi: 10.1016/j.ajo.2008.08.026. Epub 2008 Oct 18.

DOI:10.1016/j.ajo.2008.08.026
PMID:18930447
Abstract

PURPOSE

To provide an update and review of femtosecond (FS) lasers in clinical ophthalmology.

DESIGN

Perspective, literature review, and commentary.

METHODS

Selected articles from the literature and the authors' clinical and laboratory studies.

RESULTS

The FS laser employs near-infrared pulses to cut tissue with minimal collateral tissue damage. Although its major use at present is in the cutting of laser in situ keratomileusis flaps, the laser has proven its versatility in laser-assisted anterior and posterior lamellar keratoplasty, cutting of donor buttons in endothelial keratoplasty, customized trephination in penetrating keratoplasty, tunnel creation for intracorneal ring segments, astigmatic keratotomy, and corneal biopsy. Current laboratory studies include all-FS laser refractive keratomileusis sans flap, cutting corneal pockets for insertion of biopolymer keratoprostheses, noninvasive transscleral glaucoma surgery, retinal imaging and photodisruption, presbyopia surgery, and anterior lens capsulorrhexis.

CONCLUSIONS

Advances in ultra-fast laser technology continue to improve the surgical safety, efficiency, speed, and versatility of FS lasers in ophthalmology.

摘要

目的

对飞秒(FS)激光在临床眼科中的应用进行更新和综述。

设计

观点阐述、文献综述及评论。

方法

从文献以及作者的临床和实验室研究中选取文章。

结果

飞秒激光利用近红外脉冲切割组织,对周围组织的损伤最小。尽管其目前主要用于制作准分子原位角膜磨镶术(LASIK)瓣,但该激光已在激光辅助前、后板层角膜移植术、内皮角膜移植术中切割供体植片、穿透性角膜移植术中定制环钻、角膜内环植入术的隧道创建、散光性角膜切开术以及角膜活检等方面证明了其多功能性。当前的实验室研究包括无瓣全飞秒激光屈光性角膜切削术、为植入生物聚合物角膜假体而切割角膜袋、无创性经巩膜青光眼手术、视网膜成像和光破碎、老花眼手术以及晶状体前囊撕开术。

结论

超快激光技术的进展持续提高飞秒激光在眼科手术中的安全性、效率、速度和多功能性。

相似文献

1
Femtosecond lasers in ophthalmology.眼科中的飞秒激光。
Am J Ophthalmol. 2009 Feb;147(2):189-197.e2. doi: 10.1016/j.ajo.2008.08.026. Epub 2008 Oct 18.
2
Femtosecond laser-assisted corneal surgery.飞秒激光辅助角膜手术
Curr Opin Ophthalmol. 2007 Jul;18(4):295-9. doi: 10.1097/ICU.0b013e3281a4776c.
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Femtosecond laser technology in corneal refractive surgery: a review.飞秒激光技术在角膜屈光手术中的应用:综述。
J Refract Surg. 2012 Dec;28(12):912-20. doi: 10.3928/1081597X-20121116-01.
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Short-term results of penetrating keratoplasty performed with the Femtec femtosecond laser.使用Femtec飞秒激光进行穿透性角膜移植术的短期结果。
Am J Ophthalmol. 2008 Jul;146(1):50-55. doi: 10.1016/j.ajo.2008.02.025. Epub 2008 Apr 24.
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Orientation teeth in nonmechanical femtosecond laser corneal trephination for penetrating keratoplasty.
Am J Ophthalmol. 2008 Jul;146(1):46-49. doi: 10.1016/j.ajo.2008.02.012. Epub 2008 Apr 9.
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[Femtosecond laser application in keratoplasty--current view].[飞秒激光在角膜移植术中的应用——当前观点]
Klin Oczna. 2008;110(4-6):207-10.
7
Top-hat shaped corneal trephination for penetrating keratoplasty using the femtosecond laser: a histomorphological study.使用飞秒激光进行穿透性角膜移植术的礼帽形角膜环钻术:一项组织形态学研究
Cornea. 2009 Aug;28(7):795-800. doi: 10.1097/ICO.0b013e31819839c6.
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Femtosecond laser-assisted corneal surgery.飞秒激光辅助角膜手术。
Curr Opin Ophthalmol. 2010 Jul;21(4):288-92. doi: 10.1097/ICU.0b013e32833a8dbc.
9
Real-time optical coherence tomography-guided femtosecond laser sub-Bowman keratomileusis on human donor eyes.人供体眼上的实时光学相干断层扫描引导的飞秒激光前弹力层下角膜磨镶术
Am J Ophthalmol. 2008 Jul;146(1):42-5. doi: 10.1016/j.ajo.2008.03.003. Epub 2008 Apr 24.
10
Applications of femtosecond lasers in ophthalmic surgery.飞秒激光在眼科手术中的应用。
Expert Rev Med Devices. 2013 Jan;10(1):115-24. doi: 10.1586/erd.12.59.

引用本文的文献

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Effect of Clear Corneal Incisions via Femtosecond Laser Versus Manual Incisions on Corneal Aberrations in Cataract Surgery.飞秒激光与手动切口的透明角膜切口对白内障手术中角膜像差的影响
Micromachines (Basel). 2025 Aug 15;16(8):939. doi: 10.3390/mi16080939.
2
Femtosecond Laser-Assisted Donor and Recipient Preparation for Bowman Layer Transplantation.飞秒激光辅助的前弹力层移植供体和受体准备
J Clin Med. 2025 Jun 19;14(12):4362. doi: 10.3390/jcm14124362.
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Femtosecond Laser Direct Writing of Diffraction Gratings for Modifying the Refractive Index of Intraocular Lenses.
用于改变人工晶状体折射率的飞秒激光直接写入衍射光栅
ACS Omega. 2025 May 1;10(18):18596-18604. doi: 10.1021/acsomega.4c11380. eCollection 2025 May 13.
4
To study the anatomic and intraoperative factors responsible for gas bubble migration in the anterior chamber during femtosecond laser-assisted in situ keratomileusis (FS-LASIK) flap creation.研究飞秒激光原位角膜磨镶术(FS-LASIK)制作角膜瓣过程中前房气泡迁移的解剖学及术中相关因素。
Indian J Ophthalmol. 2025 Jul 1;73(7):1000-1004. doi: 10.4103/IJO.IJO_3098_23. Epub 2025 Apr 17.
5
Intraoperative Optical Coherence Tomography (OCT)-Guided Femtosecond Laser-Assisted Descemet Membrane Endothelial Keratoplasty (iFAD).术中光学相干断层扫描(OCT)引导的飞秒激光辅助Descemet膜内皮角膜移植术(iFAD)。
Bioengineering (Basel). 2024 Nov 25;11(12):1192. doi: 10.3390/bioengineering11121192.
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Advances in Transepithelial Photorefractive Keratectomy versus Laser-Assisted In Situ Keratomileusis.经上皮光性角膜切削术与准分子原位角膜磨镶术的进展
Diagnostics (Basel). 2024 Feb 23;14(5):481. doi: 10.3390/diagnostics14050481.
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Advantages of femtosecond laser in various corneal transplantation procedures: A narrative literature review.飞秒激光在各种角膜移植手术中的优势:一篇叙述性文献综述。
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The role of lanthanide luminescence in advancing technology.镧系元素发光在推动技术发展中的作用。
RSC Adv. 2023 Jun 13;13(26):17787-17811. doi: 10.1039/d3ra00991b. eCollection 2023 Jun 9.
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Commentary: Ophthalmic medicine and surgery on the nanoscale: More than just a pipe dream.评论:纳米尺度下的眼科医学与手术:不止是白日梦。
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Femtosecond Laser-Assisted Cataract Surgery versus Conventional Phacoemulsification Surgery: Clinical Outcomes with EDOF IOLs.飞秒激光辅助白内障手术与传统超声乳化白内障手术:使用扩展景深人工晶状体的临床结果
J Pers Med. 2023 Feb 24;13(3):400. doi: 10.3390/jpm13030400.